Bile fact sheet:

                                                                                                                                                                    

Noun 1. bile - a digestive juice secreted by the liver and stored in the gallbladder; aids in the digestion of fats
digestive fluid, digestive juice - secretions that aid digestion

 The liver is crisscrossed with a densely packed web of blood vessels and special pathways called bile ducts. Liver cells are called hepatocytes. The blood enters through the portal vein and the hepatic artery. It leaves by way of the hepatic vein. Tucked beneath the liver towards the right side is a pear-shaped organ called the gall bladder, whose main function is to store and concentrate bile. The gall bladder is connected to the liver by way of biles ducts. Bile is collected in the liver bile ducts and transported to the gallbladder, where it is concentrated and stored .

Medical Encyclopedia

Secretion of Bile and the Role of Bile Acids In Digestion

Bile salts are reabsorbed by the last portion of the small intestine, extracted by the liver, and resecreted into bile. This recirculation of bile salts is known as the enterohepatic (Of or involving the intestine and liver.) circulation.    Enterohepatic recirculation is the process by which a drug is reabsorbed in the gastrointestinal track (GIT) after biliary excretion.

Effect of fasting on the enterohepatic circulation of bile acids ...

Bilirubin (the main pigment in bile) is excreted in bile as a waste product of destroyed red blood cells, giving stool a green-brown color. SOURCE = RBC

Drugs and other waste products are excreted in bile and later eliminated from the body.

bilirubin

Bilirubin is the waste product that results from the breakdown of hemoglobin molecules from worn out red blood cells. Ordinarily, it is excreted from the body as the chief component of bile. Excessive levels of bilirubin stain the fatty tissues in the skin yellow; this condition is called jaundice. Very high levels of bilirubin in the bloodstream can cause permanent damage to certain areas of the brain of newborn infants - kernicterus. This can cause a characteristic form of crippling known as athetoid cerebral palsy. To prevent this from happening, bilirubin levels are monitored in newborns, and excessive levels of bilirubin are treated by either phototherapy ("bilirubin lights") or exchange transfusion.

 

Bilirubin  is the main bile pigment that is formed from the breakdown of heme in red blood cells.  The presence of drugs that interfere with glucuronyl transferase impairs the liver's ability to conjugate bilirubin - inability to conjugate bilirubin results in high circulating levels of unconjugated bilirubin, which, if untreated, passes through the blood-brain barrier and can produce encephalopathy.
 

bile - Definition of bile by Webster's Online Dictionary - a yellowish green fluid made by the liver from bile salts, bilirubin (broken down red blood cells), cholesterol, and other substances; the fluid stored in the gallbladder; the fluid released from the gallbladder into the intestine to help fat digestion
 

 

YELLOW BILE - Definition

Another problem that can arise is the loss of bacteria that the intestines need. These good bacteria may be wiped out when antibiotics are used.

Bilirubin is a breakdown product of hemoglobin.

http://web.archive.org/web/20041109162306/http://www.rnceus.com/lf/lfbili.html

The inability to conjugate bilirubin results in high circulating levels of unconjugated bilirubin, which, if untreated, passes through the -brain barrier and can produce encephalopathy. bile

 

BILE - A greenish-yellow fluid secreted by the liver and stored in the gallbladder. Bile plays an important role in the intestinal absorption of fats. Bile is secreted by the liver and contains cholesterol, bile salts, and waste products such as bilirubin. Bile salts aid in the digestion of fats. Bile passes out of the liver via the bile duct where it is stored in the gallbladder and released in response to a fat-containing meal.

 

Complications include hepatic failure with its attendant complications such as bleeding, vomiting of blood, accumulation of fluid in the abdomen (ascites), and a condition called hepatic encephalopathy where the patient has altered consciousness and later coma.

 

The yellow colouration is caused by an excess amount of the bile pigment known as bilirubin in the body.



Jaundice

Introduction
Cause and Pathogenesis
Symptoms and Signs
Investigations and Diagnosis
Treatment and Prognosis
Prevention
 

 

 

Portal Hypertension: Portal hypertension is a serious health complication.
Blood flows into the liver from the intestines through the portal vein. Damage from cirrhosis slows the flow of through this vein, causing a condition known as portal hypertension. pressure in the portal vein rises as the flow slows, and the flows back into the stomach and esophageal vessels, which are not designed to move large quantities of . These vessels then enlarge, become contorted due to the increase in pressure and the thin walls of the veins, and develop into varices (Latin for "twisted vein"). If varices burst under the pressure, life-threatening bleeding can occur in the esophagus or stomach.

Portal Hypertension
... As the portal pressure increases, more blood flows into the liver ... reabsorbed by the
intestines, such as bile acids ... impact of liver disease on the blood levels of ...
home3.inet.tele.dk/omni/portal_hypertension.htm - 26k - Cached

 

Liver, Biliary, & Pancreatic Disorders - The Liver: Anatomy and ...
... from the hepatic artery; nutrient-rich blood flows in from ... blood and excretes a product
called bile, which helps ... The liver processes this blood and breaks down ...
www.uuhsc.utah.edu/healthinfo/adult/Liver/liver.htm - 7k - Cached

 

 

Gall Bladder and Bile
... The liver is crisscrossed with a densely packed web of blood vessels and special
pathways called bile ducts. Liver cells are called hepatocytes. ...
www.innvista.com/health/anatomy/gallblad.htm - 6k - Cached

HepNet - The Liver in Health
... a pear-shaped bag), and then it flows through the cystic duct into the common bile
duct and ... The portal vein supplies blood (from the portal system, the ...
www.hepnet.com/liver/health.html - 14k - Cached

 

 

 

 

In a person with Gilbert's syndrome, the bilirubin levels typically fluctuate up and down

 

Bile is  substance produced by the liver, and concentrated and stored in the gallbladder. Bile contains many different substances, including bile salts, cholesterol, and bilirubin. After a meal, the gallbladder pumps bile into the duodenum (the first part of the small intestine) to keep the intestine's contents at the appropriate pH for digestion, and to help break down fats.


 

 

 

In a person with Gilbert's Syndrome , the bilirubin levels typically fluctuate up and down.   It is not clear whether the symptoms are directly related to higher levels of bilirubin.


... Gilbert's syndrome is a common, often inherited disorder that affects processing
by the liver of the greenish-brown pigments in bile (called bilirubin). ...
www.bdf.org.uk/leaflets/gilbert.html - 8k - Cached -

 

Bile is  substance produced by the liver, and concentrated and stored in the gallbladder. Bile contains many different substances, including bile salts, cholesterol, and bilirubin. After a meal, the gallbladder pumps bile into the duodenum (the first part of the small intestine) to keep the intestine's contents at the appropriate pH for digestion, and to help break down fats.
 

 

  • Symptoms of Cirrhosis of the liver - WrongDiagnosis.com
    Symptoms and Complications Associated with Cirrhosis In its ... skin, giving it the classic yellowish tinge ... Gallstones: If cirrhosis prevents bile from draining at ...
     


       

      tpan.com - Preventing or Managing Drug Side Effects. Protease inhibitors may increase the level of bilirubin in the . (Bilirubin is the yellowish pigment in bile associated with jaundice.) .

       

      Common Bile Duct Exploration

      ... Index Illustration Common Bile Duct Exploration. What is a common bile duct exploration? ... How do I prepare for a common bile duct exploration? ...
      www.medformation.com/ac/ crswa.nsf/wha/wha_commbd_crs.htm - 11k - Cached

       

      Bile-coloured urine is typically seen in jaundice; it indicates an abnormal retention of bile.
      Blue urine may result from the presence of indigo or of methylene blue (used as an antidote to certain types of poisoning). 
      Black urine can indicate the presence of a pigmented cancerous tumour or carbolic acid poisoning.
      On the other hand, very pale urine, which results from its being extremely dilute, may be a pointer to diabetes insipidus.