For most of its life cycle the bacteriophage called Phi-X-174 has
the curious property that its DNA is circular, i.e. has its
ends joined, and is single stranded. During reproduction however it is
double-stranded (and presumably still circular) giving it the
classical "double helix" shape, which raises the following question.
Is it topologically equivalent to a cylinder or a Moebius band?
Since DNA has 5 base pairs for every 180 degree twist and Phi-X-174
has 5375 base pairs it has 1075 twists (prior to the
join) which is an odd number of half-turns and so it is equivalent to
a Moebius band.
This is a perfect example of a mathematician making inferences
in a field of study about which he has almost no knowledge.
As a result the statements are almost surely false ... none-the-less
see Topology in biology for
marginally more detail.
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