Item List
| Item Name | Price | Location | Effect | Cheat Code # |
| Antidote | 100 | Mart | Removes POISON | 0B |
| Awakening | 250 | Mart | Removes SLEEP | 0E |
| Bicycle | 1000000 | Bike Shop | 2x travel speed, access to Cycling Road | 2D |
| Bike Voucher | Vermillion | Free bike! | 06 | |
| Burn Heal | 250 | Mart | Removes BURN | 0C |
| Calcium | 9800 | Celadon Store | Increases Special permanently | 27 |
| Carbos | 9800 | Celadon Store | Increases Speed permanently | 26 |
| Card Key | Silph Co. | Opens Silph Co. Locked Doors | 30 | |
| Coin | Celadon | Slot machine money | 3B | |
| Coin Case | Celadon | Needed to get/buy/use coins | 45 | |
| Dire Hit | 650 | Celadon | Increase one attack's effect(s) | 3A |
| Dome Fossil | Mt. Moon | Want a Kabuto? | 29 | |
| Elixir | Varies | Recover 10 PP for all attacks | 52 | |
| Escape Rope | 550 | Mart | Teleport back to the last visited Pokémon Center | 1D |
| Ether | Varies | Recover 10 PP for 1 attack | 50 | |
| Exp. All | Route 15 | Shares experience with other Pokémon | 4B | |
| Fire Stone | 2100 | Celadon Store | Evolves some Pokémon | 20 |
| Fresh Water | 200 | Celadon Store | Recover 50 HP | 3C |
| Full Heal | 500 | Mart | Removes conditions | 34 |
| Full Restore | 3000 | Mart | All HP recovery, remove conditions | 10 |
| Gold Teeth | Safari Zone | Trade for HM04 | 40 | |
| Good Rod | Fuchisa | Can catch Magikarp or Goldeen | 4D | |
| Great Ball | 600 | Mart | Catch Pokémon with this | 03 |
| Guard Spec | 700 | Mart | Disable enemy's special attacks | 37 |
| Helix Fossil | Mt. Moon | Want a Omanyte? | 2A | |
| HP Up | 9800 | Celadon Store | Add 1 HP point to max HP | 23 |
| Hyper Potion | 1500 | Mart | Recovers 200 HP | 12 |
| Ice Heal | 250 | Mart | Removes FROZEN | 0D |
| Iron | 9800 | Celadon Store | Increases defense permanently | 25 |
| Item Finder | Route 11 | Beeps when secret items are near | 47 | |
| Leaf Stone | 2100 | Celadon Store | Evolves some Pokémon | 2F |
| Lemonade | 350 | Celadon Store | Recovers 80 HP | 3E |
| Lift Key | Game Corner | Activates Basement Elevator | 48 | |
| Master Ball | Silph Co. | Capture any Pokémon | 01 | |
| Max Elixir | Varies | Recover all PP | 53 | |
| Max Ether | Varies | Recover all PP to one attack | 51 | |
| Max Potion | 2500 | Mart | Recover all HP | 11 |
| Max Repel | 700 | Mart | No random attacks for a while | 39 |
| Max Revive | Varies | Revive and recover all HP | 36 | |
| Moon Stone | Varies | Evolves some Pokémon | 0A | |
| Nugget | Varies | Sell it for 5000 bucks | 31 | |
| Oak's Parcel | Viridian Mart | Trade it for the Pokédex | 46 | |
| Old Amber | Museum | Want an Aerodactyl? | 1F | |
| Old Rod | Vermillion | Can catch Magikarp | 4C | |
| Paralyze Heal | 200 | Mart | Removes PARALYZE | 0F |
| Pokéball | 200 | Mart | Capture Pokémon with this | 04 |
| Poké Doll | 1000 | Celadon Store | Distract enemies | 33 |
| Poké Flute | Pokémon Tower | Wake up anyone (including Snorlax) | 49 | |
| Pokédex | Prof. Oak | Store data (not really an item) | None | |
| Potion | 300 | Mart | Recover 20 HP | 14 |
| PP Up | Varies | Add 1 HP point to max PP for one attack | 32 | |
| Protein | 9800 | Celadon Store | Increases attack permanently | 24 |
| Rare Candy | Varies | Automatic exp. level up | 28 | |
| Repel | 350 | Mart | No random attacks for a while | 1E |
| Revive | 1500 | Mart | Revives Pokémon | 35 |
| S. S. Ticket | Sea Cottage | Entrance ticket to the S.S. Anne | 3F | |
| Safari Ball | Safari Zone | Equal to a Great Ball | 08 | |
| Secret Key | Cinnabar Mansion | Key to Cinnabar Gym | 2B | |
| Silph Scope | Game Corner | Identify ghosts | 48 | |
| Soda Pop | 300 | Celadon Store | Recovers 60 HP | 3D |
| Super Potion | 700 | Mart | Recovers 50 HP | 13 |
| Super Repel | 500 | Mart | No random attacks for a while | 38 |
| Super Rod | Route 12 | Can catch various water Pokémon | 4E | |
| Thunder Stone | 2100 | Celadon Store | Evolves some Pokémon | 21 |
| Town Map | Gary's House | Map of the game's overworld | 05 | |
| Ultra Ball | 1200 | Mart | Capture Pokémon with this | 02 |
| Water Stone | 2100 | Celadon Store | Evolve some Pokémon | 22 |
| X Accuracy | 950 | Celadon Store | Increases accuracy in battle | 2E |
| X Attack | 500 | Celadon Store | Increases attack in battle | 41 |
| X Defend | 550 | Celadon Store | Increases defense in battle | 42 |
| X Special | 350 | Celadon Store | Increases special power in battle | 44 |
| X Speed | 350 | Celadon Store | Increases speed in battle | 43 |