Hannah and her family are inspired by:

Susan la Flesche-Picotte inspired Hannah's creation. She was an amazing woman on a mission and everyone should learn more about her. She decided to become a doctor after a white man refused to treat an Indian woman who was in great pain.

Chief Iron Eye was Susan's father, and so is he Hannah's in his House of Cards incarnation. Chief Iron Eye continued the tradition of polygomy in his tribe, while walking a fine line with the Christain Church. Late in his life, after he married a young woman of the tribe, he converted - and as a concession to his new faith he annulled the marriage. He kept all the wives he'd had children with though, and it appears the church was either fine with that or looked the other way. (There is one rumor I found online, which I haven't been able to find again, that says he then adopted the youngest wife.)

Yvette la Flesche-Tibbles was Susan's remarkable sister, often referred to as Susette and called such in game. She spoke before Congress and toured Europe with her husband, a journalist, educating the influential about the situation of the natives in America.

Francis la Flesche, or Frank, as you will hear Hannah call him in game, inspired Hannah's little brother. In 1879 La Flesche accompanied his sister, Susette, and uncle, Ponca chief Standing Bear, on their grueling Eastern crusade for Indian land reform, and took a job a year later as a copyist for the Bureau of Indian Affairs, working at night to complete two law degrees. He later became an anthropologist in experience. He wrote a book (with 4 volumes) on the Osage Tribe. While some documents refer to Iron Eye as the last chief of the Omaha, others refer to Susan as the last, and still others to Frank.

Hannah's Tribe are inspired by the American Omaha, who still retain their ancestral lands. Their cousin tribe is the Ponca, whose 'relocation' started Susette on her personal crusade.