Tennessee State Route 181 is a north-south highway in Western Dyer County. This highway runs along the Mississippi River. It is also the Great River Road. TN St Rt 181 does not pass through any towns in Dyer County. TN St Rt 181 is multi-plexed in Dyer County. The Great River Road, through Dyer County.
TN St Rt 181 intersects the following highways in Dyer County. Tennessee State Route 103, near Miston. Interstate 155, near Lenox. U.S. Rt. 412, near Lenox. Tennessee State Route 104, near Heloise.
BGS on EB I-155/U.S. Rt. 412. NB TN St Rt 181 near I-155/U.S. Rt. 412.
