Tennessee State Route 22 runs east-west across Obion County. It runs from the Lake/Obion County Line east to Union City, via the northern regions of Obion County. East of Union City, TN St Rt 22 becomes freeway into Weakley County. TN St Rt 22 passes through the following towns in Obion County. Samburg Fremont Old Fremont Union City TN St Rt 22 is multi-plexed in Obion County. Tennessee State Route 21, near Lassiter Corner. Tennessee State Route 5, near Union City. U.S. Rt. 51, at Union City. Tennessee State Route 3, at Union City. Tennessee State Route 184, at Union City. Tennessee State Route 45W, at Union City. TN St Rt 22 intersects the following highways in Obion County. Tennessee State Route 21, near Lassiter Corner. Tennessee State Route 157, near Clayton. Tennessee State Route 5, near Union City. U.S. Rt. 51, at Union City. Tennessee State Route 3, at Union City. Tennessee State Route 5, at Union City. U.S. Rt. 51, at Union City. Tennessee State Route 3, at Union City. Tennessee State Route 184, at Union City. U.S. Rt. 45W, at Union City. Tennessee State Route 21, at Union City. U.S. Rt. 45W, at Union City. Tennessee State Route 184, at Union City. Tennessee State Route 431, near Union City.
A guide marker in Union City. A BGS on NB U.S. Rt. 51.
