U.S. Federal Route 70 runs east-west across Knox County. This is one of the main surface routes in the Downtown Knoxville area. U.S. Rt. 70 passes through the following towns in Knox County. Farragut Knoxville U.S. Rt. 70 is multi-plexed in Knox County. U.S. Rt. 11, from the Loundon/Knox County Line to the eastside of Knoxville. Tennessee State Route 1, from the Loundon/Knox County Line to the eastside of Knoxville. U.S. Rt. 441, at Knoxville. Tennessee State Route 33, at Knoxville. U.S. Rt. 11E, near Knoxville. U.S. Rt. 25W, near Knoxville. U.S. Rt. 70 intersects the following highways in Knox County. Tennessee State Route 332, near Farragut. Interstate 140, near Farragut. Tennessee State Route 332, near Knoxville. Tennessee State Route 158, at Knoxville. U.S. Rt. 129, at Knoxville. Tennessee State Route 115, at Knoxville. U.S. Rt. 441, at Knoxville.
