PMS. What It Is and How You Can Beat It.
                         By Lewis E. Sullivan, M.D., FACOG
 

                         Kim H. sat in my office nervously twisting a tissue in her fingers.
                         She seemed on the verge of tears. Kim is an attractive 32 year old
                         bank executive. Her husband, Frank, is a successful general
                         contractor. They have two children. The last child I had delivered
                         about two years ago. She had requested this consultation because in
                         her words, "Doctor, I think I'm losing my mind. It seems lately that
                         I get so angry at everything. I love Frank but I get so angry with
                         him. He says I always pick on him and nothing he says or does
                         seems to make any difference. I 'm even angry at the kids. A few
                         days ago, Jeff, my two year old spilled something which he always
                         does and I went ballistic. I ran out of the room shaking because I
                         just knew if I stayed I could really hurt him. I guess Frank's right I
                         need to see a psychiatrist." Further history taking revealed that Kim's
                         sex life was also suffering. "I used to love it when Frank would
                         come up behind me and fondle my breasts. I knew that he still
                         desired me and that made me feel wonderful. Now my breasts are
                         so sore I can't stand to wear a bra some days much less have them
                         touched and with this cramping and bloating forget about sex."
                         Kim's weight was also bothering her. She continued, "I can't seem
                         to get enough chocolate. I could eat two or more candy bars at a
                         sitting. I never used to be that way. I'm starting to gain weight,
                         sometimes a couple of pounds overnight." Her physical examination
                         was entirely normal. I made some suggestions and asked that she
                         come back in three months.

                         Kim returned appearing less anxious. She said that the daily diary of
                         how she felt revealed that she was worse about a week before her
                         period started. Once she started her menses she felt "normal" again.
                         "I guess that means I am really crazy, right?" I explained that she
                         was not crazy. What she described was a classic case of PMS or
                         premenstrual syndrome. She volunteered that she had started
                         walking with Frank almost every night. Kim changed her diet. She
                         ate more healthy foods and ate less food at more frequent intervals.
                         The supplements I had suggested seemed to be working and Frank
                         said she seemed like her old lovable self again. We agreed that she
                         would report on her progress by phone.

                         Several studies estimate that PMS effects six out of ten women.
                         Flares of acne, abdominal bloating and cramps, as well as changes in
                         libido, headaches (including migraine) and craving salty foods are
                         common. Symptoms range from mild to severe. Depression and
                         anger can border on full blown psychosis. It is important to
                         remember that PMS symptoms practically disappear when the
                         menses starts. Anger, rage or depression that is present all the time
                         is not part of this syndrome. In such cases the woman might wish
                         to seek a consultation with her healthcare provider.

                         The exact cause or causes of PMS are unknown. We do know that
                         PMS is a real physical disorder and not just part of being a woman.
                         Many researchers have shown that whatever the cause it rests
                         within the woman's ovaries. PMS symptoms abruptly stop when
                         ovaries are removed or inactivated by drugs or disease. Dr. Katarina
                         Dalton, in England in the early 1960s, pioneered the theory that PMS
                         resulted from a deficiency of progesterone, the second of two major
                         female hormones. She obtained success when she supplemented her
                         patients with extra progesterone. Dr. Dalton discovered, as have
                         many other since then, that the progesterone must be "natural"
                         progesterone not synthetic. Birth control pills and the drug Provera
                         contain synthetic progesterones called "progestins." Researchers,
                         including Dr. Dalton, found that synthetics often made PMS worse.
                         This accounts for some women stopping the "pill" to avoid their
                         PMS symptoms.

                         Both natural and synthetic progesterones come from a wild Mexican
                         yam. Natural progesterone is chemically identical to human
                         progesterone. Progestins only closely resemble the human form.
                         Natural progesterone, when swallowed, loses most of its potency
                         through liver metabolism. This requires a much larger and therefore
                         more costly amount of hormone to provide therapeutic blood levels.
                         Progestins do not share this problem.

                         Today you can buy natural progesterone in a cream form to rub into
                         your skin. The trade name is ProgestaCare and it is available for
                         vaginal insertion. Finally, the FDA recently approved for sale oral
                         capsules of natural micronized progesterone called Prometrium.
                         These come in 100 mg capsules to take twice a day. All of these are
                         rather expensive.

                         Modern research proved that depression comes from an imbalance
                         of brain neurotransmitter hormones called serotonins. Popular
                         antidepressants such as Prozac have proven to be miracle cures for
                         not only moderate to severe depression, but also the anger or rage of
                         PMS. Your healthcare provider can give you specific information on
                         dosage, side effects and contra indications.

                         Luckily, most women with PMS can receive effective treatment that
                         is more natural and much less expensive. First, you must keep a
                         daily diary or chart of how you feel over three months. To be PMS,
                         your symptoms must concentrate in the seven to ten days preceding
                         your period. Remember a cycle starts with the first day of flow and
                         goes until the first day of the next month's flow. The days from
                         your ovulation until you start menses are a constant of fourteen
                         days. So if you have twenty-eight day cycles, your symptoms will
                         start on or after the fourteenth day. On the other hand if you have,
                         say, a thirty-two day cycle your start day will be on or after day
                         eighteen.

                         For unknown reasons, women with PMS demonstrate either a
                         deficiency or perhaps a resistance to certain vitamins and minerals.
                         Calcium and magnesium are also often low in PMS women. The
                         average diet gives about 300 or 400 mg of calcium a day. You need
                         doses of 1200 to 1400 mg for the best results. Four Tums EX or six
                         regular Tums per day can supply this amount easily and cheaply.
                         You also need 400 units of vitamin D to properly absorb the
                         calcium. Too much calcium can result in kidney stones and
                         disorders so don't exceed recommended doses. Magnesium is
                         available in 50 mg tablets. Doses of 200 mg per day are considered
                         safe. Take with or after food because it can upset the stomach.
                         Vitamin B-6 in doses up to 600 mg per day are often useful. Start at
                         100 mg and increase by 100 mg every three or four days until
                         effective. Avoid doses above 800 mg as toxicity can occur. B-6 is a
                         mild diuretic and helps to relieve bloating and water retention. Divide
                         B-6 into several doses throughout the day with the largest at
                         bedtime. Breast tenderness frequently responds to vitamin E in 800
                         unit doses. If your symptoms are mild you may get these additional
                         vitamins and minerals from diet alone. Dietitians and nutritionists can
                         supply you with a list of food sources.

                         For cramping and muscle aches, try over the counter NSAID pain
                         relievers such as Aleve or Motrin-IB. If one brand is not effective
                         try another. People can react differently to these medications. Be
                         sure to follow the suggested dosages on the bottle.

                         Finally, large muscle exercise can relieve stress and help with
                         depression. Walking, jogging, swimming or bike riding can relieve
                         many symptoms. Avoid food cravings. Folklore has it that if we
                         crave something our body must need it. That is simply not true.
                         Much of the fatigue in PMS is the result of rapidly rising and falling
                         blood sugar levels. Eating four to six small meals a day rather than
                         three can help stabilize glucose levels. Avoid high sugar foods like
                         candy, sodas and chocolate. Concentrate on whole wheat foods,
                         pasta, low fat proteins like fish and tofu. The same avoidance goes
                         for alcohol and caffeine products. Alcohol acts like a sugar and
                         caffeine adding to the general stress and anxiety levels. Avoid salty
                         foods like cheese, soups, smoked meats and fish, nuts, soy sauce
                         and Oriental foods as they are all high in salt. Your body only stores
                         salt water. Plain water is easily excreted by the kidney. Drink lots of
                         plain water to aid in bloating and water retention.

                         So there you have it. By adjusting your diet, adding exercise and
                         taking a few supplemental vitamins and minerals most of you will do
                         very well. For others with more severe symptoms, there are
                         progesterone supplements or perhaps Prozac. The good news is that
                         you can do something about the spectrum of symptoms of PMS.
                         You can gain back your self-control. You can fight and win your
                         battle to lessen and even eliminate PMS from your life.