Affymetrix-technology for acquiring, analyzing and managing complex genetic information for use in biomedical research, genomics and clinical diagnostics. AFFX (NASDAQ)
Agouron Pharmaceuticals, Inc.-pharmaceutical company; discovery, development, manufacturing, and marketing of small-molecule drugs engineered to inactivate proteins that play key roles in cancer, AIDS, and other diseases. AGPH (NASDAQ)
Alliance Pharmaceutical Corp.-research and development company focused on transforming innovative scientific discoveries into novel therapeutic and diagnostic agents. ALLP (NASDAQ)
AlphaGene, Inc.-bioinformatics and functional genomics, technologies for gene and protein target discovery to accelerate drug development for major human diseases, gene libraries containing high quantities of full-length cDNA (genes). /Privately Held/
Alteon Inc.-discovery and development of pharmaceutical products for the treatment of the complications of diabetes and age-related diseases. ALTN (NASDAQ)
ALZA Corporation-pharmaceutical, drug delivery technologies, applies its delivery technologies to develop pharmaceutical products with enhanced therapeutic value. AZA (NYSE)
American Biogenetic Sciences-global biopharmaceutical and diagnostic company, products in the fields of cardiology and neurobiology. MABXA (NASDAQ)
Amgen Inc.-specialized human therapeutics, research and product development in hematopoietic growth factors, neuroendocrinology, inflammation and tissue growth factors. AMGN (NASDAQ)
Antex Biologics-biopharmaceutical company developing and commercializing
therapeutic products to prevent and treat infectious diseases and related disorders; discovery and research of technologies for the development of vaccines against mucosal infections. ANTX (NASDAQ)
Ariad Pharmaceuticals, Inc.-design and development of pharmaceuticals based on intracellular signaling technology, design of small molecules that promote or inhibit the targeted intracellular interaction for a wide array of clinical applications. ARIA (NASDAQ)
ArQule, Inc.-accelerated drug discovery using its high throughput lead generation and lead optimization technologies. ARQL (NASDAQ)
Astra-pharmaceutical; respiratory, cardiovascular, gastrointestinal, pain control. (NYSE, Sweden)
Atlantic Pharmaceuticals, Inc.-development of a number of diverse pharmaceutical and biomedical products and technologies for use in cancer, infection, ophthalmic disorders, pain and inflammation, cardiovascular diseases and dermatological conditions. ATLC (NASDAQ)
Aurora Biosciences Corporation-designs and develops proprietary drug discovery systems, services and technologies, proprietary fluorescent assay technologies and an ultra-high throughput screening system ("UHTSS"). ABSC (NASDAQ)
AxyS Pharmaceuticals-merger of Arris Pharmaceutical and Sequana Therapeutics, drug discovery, identifying critical genes and selecting targets in the disease pathway, creating and screening libraries of molecules to find potential drug candidates, refining drug leads with computer-based "virtual" drug design.
BASF Health & Nutrition-supplies a wide product range of vitamins, carotenoids and omega-3 fatty acids to the world's leading pharmaceutical and food industries. Subsidiary
Bayer Corporation-$9 billion, research-based company with major businesses in health care and life sciences, chemicals and imaging technologies. Subsidiary
Biogen-biotechnology company principally engaged in developing genetically-engineered human pharmaceuticals.
Bio-Rad Laboratories -life science research products, clinical diagnostics and
analytical instruments used in healthcare,
scientific investigation and industry.
Boehringer Ingelheim Village-operate in the pharmaceutical, biological and chemical sectors, rank among the top 20 pharmaceutical companies in the world. /Privately Held/
Boston Biomedica, Inc.- diagnostic test kit components, together with innovative, state-of the-art quality control products and services for the international biomedical industry. BBII (NASDAQ)
Bristol-Myers Squibb Company-worldwide medicines, nutritionals & medical devices and beauty care, health and personal care products. BMY (NYSE)
Cadus Pharmaceutical Corp.- development of drug discovery technologies that are based on genetically-engineered yeast and mammalian cells, unique and proprietary ability to insert human genes into yeast cells to create hybrid cells. KDUS (NASDAQ)
Cambridge NeuroScience, Inc.- ion-channel blockers that prevent nerve cell death in acute neurological disorders such as stroke, traumatic brain injury and pain; and growth factors that prevent nerve degeneration in chronic conditions such as multiple sclerosis, peripheral nerve damage, and chronic pain. CNSI (NASDAQ)
Cell Genesys, Inc.- development and commercialization of gene therapies to treat major life threatening diseases, including cancer and AIDS; developing both ex vivo (modification of cells outside the patients body) and in vivo (modification of cells within the patients body) approaches to gene therapy. CEGE (NASDAQ)
Cellomics, Inc.- drug discovery; delivering a cell-based screening platform that automates target validation and lead optimization usingfluorescence-based assays. Private
Centocor, Inc.- development and commercialization of therapeutic and diagnostic products to meet critical human health care needs, cardiovascular, infectious and autoimmune diseases, and cancer. CNTO (NASDAQ)
Cephalon, Inc.-discovery, development and marketing of innovative products to treat neurological disorders. CEPH (NASDAQ)
Cepheid -application of break-through microfluidics and microelectronics technologies to test systems based on DNA technology. Private
Chiron Corporation- diagnostics, including immunodiagnostics, critical care diagnostics and new quantitative probe tests; therapeutics, with an emphasis on oncology and infectious disease; pediatric and adult vaccines; world's second largest biotech company. CHIR (NASDAQ)
Chugai Pharma. Europe Ltd.-prescription pharmaceuticals, Japanese market for nonprescription products, DNA probes and enzyme-immunoassay (EIA) diagnostics, targeting cancer and infectious diseases, bone metabolic and hematological disorders, and cardiovascular and cerebrovascular diseases.
Clontech-PCR and PCR-based
technologies; cDNA technologies;
gene analysis; expression systems including retroviral expression; two
hybrid technologies; reporter systems; apoptosis detection; and nucleic acid
chemistry. /Privately Held/
CoCensys, Inc.-biopharmaceutical company that discovers and
develops products to treat neurological and psychiatric disorders. COCN (NASDAQ)
Compugen-designs, develops, and markets proprietary bioinformatics solutions that enhance the ability of pharmaceutical and biotech teams to extract meaningful information from genomic and protein sequence data, and accelerate the discovery of new drug leads. /Privately Held/
Connetics Corp.-product development and commercialization, focused on bringing late-stage products to high value specialty markets; diseases of the skin and connective tissues, and its sales and marketing activities at rheumatologists and dermatologists. CNCT (NASDAQ)
Cortex Pharmaceuticals, Inc.-neuroscience company focused on the development of innovative chemical compounds called AMPAKINESª, which enhance the primary form of communication between brain regions. CORX (NASDAQ)
Corvas International, Inc.-design and development of a new generation of therapeutic agents in the fields of blood clot formation (thrombosis), inflammation, cancer and other diseases, collaboration with Pfizer, strategic alliances with Schering-Plough for the development of orally active thrombin, factor Xa and hepatitis C protease inhibitors. CVAS (NASDAQ)
Cubist Pharmaceuticals, Inc-proprietary technology to selectively inhibit protein translation in pathogenic organisms by specifically targeting essential protein-RNA interactions. CBST (NASDAQ)
CuraGen Corporation-systematic application of genomics to accelerate the discovery and development of
therapeutic and agricultural products, generate comprehensive information about gene expression, biological pathways and the potential drugs that affect these pathways. CRGN (NASDAQ)
Cytimmune Sciences, Inc.-biological response markers (BRMÕs) in
humans that are invisible to other detection systems, boosting cytokine levels, reducing undesirable biological response (cytocine) levels in persons with diseases such as septic shock, rheumatoid arthritis, and osteoporosis.
CytoTherapeutics Inc.-development of cell-based therapeutics, encapsulated-cell technology is designed to treat a number of serious diseases anddisorders of the central nervous systems, including chronic pain. CTII (NASDAQ)
Eisai Co.Ltd.-
manufacturing and marketing of pharmaceutical drugs, over-the-counter drugs, chemical/food additives and veterinary products.
Eli Lilly and Company- pharmaceutical-based health care solutions, genomics, combinatorial chemistry, molecular biology and informatics.
Endogen Inc.-comprehensive lines of cytokine, T cell receptor, cell surface marker and cell adhesion products to immunology research. (NASDAQ)
Endorex Corporation. novel cancer products and oral drug delivery (deliver vaccines, proteins, and peptides), cancer therapy: immunotherapy and natural cancer therapy
Gene Logic-proprietary genomic databases for new drug target discovery and development, a novel screening technology for identifying new drug leads, and a comprehensive bioinformatics system for analyzing, managing and integrating biological information into the drug discovery process. GLGC (NASDAQ)
Genentech, Inc.-leading biotechnology company using human genetic information to develop, manufacture and market pharmaceuticals that address significant unmet medical needs in cardiovascular, oncology and endocrinology. GNE
Genetics Institute- discovery, development and commercialization of human pharmaceuticals through recombinant DNA and other technologies, products for treatments of anemia, hemophilia, cancer, bone damage, inflammatory conditions and immune system disorders.
Genome Therapeutics Corporation-genomics, identification and functional characterization of human genes associated with major diseases, bacterial genes responsible for many serious infectious diseases, top genome sequencing facility. GENE (NASDAQ)
Genomics One Corporation.-plasmid and M13 vectors, color selection, Gap-Free DNA sequences and Ordered Genomic Libraries.
GENSET Framed Home Page-tailored genomics information to pharmaceutical companies throughout the drug lifecycle, massive manufacturing of custom-made synthetic DNA fragments.
Genzyme Corporation-develops and markets pharmaceuticals, genetic diagnostic services and diagnostic, surgical, and specialty therapeutic products, biological products for the treatment of cartilage damage, severe burns, chronic skin ulcers, and neurological disorders. GENZ (NASDAQ)
Gilead Science-infectious disease, including antivirals, antifungals and antibiotics, oncology. GILD (NASDAQ)
Glaxo Wellcome - Global-biomedical research and development, discovery in the field of prescription medicines.
HGS Homepage-discovery and early clinical development of its own drugs, derives substantial near-term and potentially, long-term revenue by providing access to its drug discovery technology to other pharmaceutical firms; technology is based on rapid discovery, DNA sequencing and demonstration of the medical utility of novel human and bacterial genes. HGSI (NASDAQ)
Immunex Corporation-biopharmaceutical company dedicated to developing immune system science to protect human health, products to patients with cancer, inflammatory and infectious diseases. IMNX (NASDAQ)
Incyte Pharmaceuticals, Inc.- the use of computers to retrieve, process, and analyze biological information for drug discovery and development; quantitative analyses, database comparisons, and computational algorithms, conducting biology in silico. INCY (NASDAQ)
Isis Pharmaceuticals, Inc.-antisense drugs, studies on sequence-specific loss of messenger RNA and protein directly correlated to therapeutic benefit, species specificity.
Johnson & Johnson-broadly-based manufacturer of health care products, as well as a provider of related services for the
consumer, pharmaceutical and professional markets. 180 operating companies in 51 countries. JNJ (NASDAQ)
Knoll AG - BASF Pharma -researches, develops, manufactures and markets drugs, bulk active ingredients and intermediates; cardiovascular, the central nervous system, oncology/immunology, and metabolism.
KPMG Peat Marwick LLP-consulting, serves health care and life sciences businesses, providers, and suppliers including medical technology, biotechnology and pharmaceutical companies. /Privately held/
Lexicon Genetics-genomics pharmaceutical company focused on the identification of novel drug targets through the large-scale definition of gene function. /Privately held/
LXR Biotechnology Inc.-research and development of innovative therapeutics designed to treat diseases through the control of apoptosis or gene-directed cell death, proprietary compounds are intended therapies for organ transplant, heart/lungbypass (cardioplegia), heart attack and ischemic stroke. LXR (AMEX)
Merck & Co., Inc.-research-driven pharmaceutical company that discovers, develops, manufactures and markets a broad range of human and animal health products and services. MRK (NYSE)
Milestone Scientific Inc.-medical and dental products company, proprietary hardware and disposable products. MS (AMEX)
Mochida Pharmaceutical Co.-development and marketing of medical electronics and equipment, ethical drugs and diagnostic reagents. Japan
Myriad Genetics Inc.-genomics company discovering important disease genes and their biological pathways, research programs in cancer, heart disease, CNS disorders, metabolic disorders and respiratory diseases. MYGN (NASDAQ)
NeXstar Pharmaceuticals, Inc.-commercial biopharmaceutical company engaged in the discovery, development, manufacture and marketing of proprietary pharmaceutical products to treat life-threatening and other serious oncological, hematological and infectious disease. NXTR (NASDAQ) (recently was bought by Gilead Science)
Novartis Pharmaceuticals Corporation-discovery and development of innovative prescription drugs used to treat a number of diseases and conditions including organ transplantation, cardiovascular diseases, schizophrenia, epilepsy, cancer, and arthritis. Subsidiary
Novo Nordisk A/S-insulin and diabetes care, manufactures and markets a variety of other pharmaceutical products, the world's largest producer of industrial enzymes. NVO (NYSE)
Nycomed Amersham Home Page-healthcare, diagnostic imaging, biotechnology supply and consumer health products. NYE (NYSE)
Oncor, Inc.-genetics and molecular biology reagents, kits, human and mouse DNA probes for fluorescence in situ hybridization (FISH).
Pfizer Inc.-research-based, global health care company, discovers and develops innovative, value-added products that improve the quality of life of people around the world; company has three business segments: health care, consumer health care and animal health. PFE (NYSE)
Pharmacia & Upjohn -research-based, pharmaceutically focused company, manufactures and markets health care and related products, and operates on a global basis.
Promega-products for the life sciences,in the following areas: Molecular Biology, Cell Biology (Signal Transduction and Cellular Regulation), Genetic Identity, Neuroscience, Clinical Research and Industrial Applications, Bioluminescence and Non-isotopic Reporter Systems, Immunology Reagent Systems
Ribozyme Pharmaceuticals, Inc,-biotechnology company formed to commercialize its ribozyme technology in the fields of human therapeutics, diagnostics, agriculture and animal health. It is also commercializing its technology for use in the identification of gene function. RZYM (NASDAQ)
Roche Group-merged with Boehringer-Mannheim, research-based healthcare groups active in the discovery, development, manufacture and marketing of pharmaceuticals and diagnostic systems, producer of vitamins and carotenoids and of fragrances and flavors.
ROHHY (NASDAQ Bulletin Board)
Santa Cruz Biotechnology-primary antibodies to a broad range of regulatory proteins involved in cell signaling, transcription factors, related protein kinases, caspase family of serine proteases, monoclonal antibodies.
SmithKline Beecham Pharmaceuticals-discovers, develops, manufactures and markets pharmaceuticals, vaccines, over-the-counter (OTC) medicines and health-related consumer products, and provides healthcare services, including disease management, clinical laboratory testing, and pharmaceutical benefit management.
Schering-Plough-research-based enterprise with prescription and over-the-counter (OTC) pharmaceuticals, health care and animal health products. SGP (NYSE)
Sequus Pharmaceuticals, Inc.-development, manufacture, and commercialization of liposomal drugs and lipid-based biopharmaceutical products primarily to treat cancer and certain fungal infections. SEQU (NASDAQ)
Signal Pharmaceuticals, Inc.-target and drug discovery company focused on identifying new classes of small molecule drugs that regulate genes and the production of disease-causing proteins. SGNL (NASDAQ)
SmithKline Beecham-healthcare companie; discovers, develops, manufactures, and markets pharmaceuticals, vaccines, over-the-counter medicines and health-related consumer products, and provides healthcare services including disease management, clinical laboratory testing, and pharmacy benefit management. SBH (NYSE)
Tularik-discovery and development of a broad range of novel drugs that act through the regulation of gene expression; disease areas: viral diseases, hypercholesterolemia, immune disorders, inflammation, bacterial diseases and obesity. Private
VIMRX Pharmaceuticals-cell therapeutics focused on treatments for cancer; research and development programs in the areas of cancer, diabetes, cardiovascular disease, wound healing and skin diseases; drug discovery. VMRX (NASDAQ)
Vysis WWW Server-innovation and commercialization of Genomic Disease Management products for the clinical assessment and management of cancer, prenatal
disorders and other genetic diseases; advanced genetic imaging workstations, nucleic acid probes and reagents. VYSI(Nasdaq)
Warner-Lambert-developer and marketer of vital prescription drugs and consumer health care products. WLA (Nasdaq)
XOMA Corporation-biopharmaceutical products to treat serious bacterial and fungal infections, infectious complications, and immune system diseases including organ transplant rejection;recombinant proteins and peptides, primarily those derived from the host-defense protein BPI (bactericidal/permeability-increasing protein). XOMA (NASDAQ)
XTL Biopharmaceuticals Ltd.-radiation chimera system where human cells or tissues function in a rodent, vehicle for developing fully human high affinity monoclonal antibodies, developing human disease models. Private