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      Universal City Animal Hospital University of Georgia Universal City, Texas M. A. McCrackin Stevenson DVM, PhD Leo Gates III, DVM Rocky Mountain Laboratories Animal Clinic of Farmers Branch National Institutes of Health Dallas, TEXAS Hamilton, Montana Jerry Murray, DVM Marshall E. Bloom, MD

        [b]After this manuscript was accepted for publication, the aurhors learned that a new assay for antibodies directed against the non-structural proteins of ADV is now commercially available through Avecon, Inc. To our knowledge, there are no published reports of the assay protocol or the sensitivity and specificity of the test. For more information, see www.avecon.com.

      ACKNOWLEDGMENTS

        The authors thank Jeff Mauldin, BA, University of Georgia, and Jim Wolfinbarger, National Institute of Allergy and Infectious Disease, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT. for technical support. They also thank the ferret owners who graciously provided samples from their pets for research purposes.


        REFERENCES

        1. Welchman DB, Oxenham M, Done SH: Aleutian disease in domestic ferrets: Diagnostic findings and survey results. Vet Rec 132:479-484, 1993.

        2. Rozengurt N, Stewart D, Sanchez S: Diagnostic exercise: Ataxia and incoordination in ferrets. Lab Anim Sci 45:432- 434, 1995.

        3. Palley LS, Corning BF, Fox JG, et at: Parvovirus-associated syndrome (Aleutian disease) in two ferrets. JAVMA 201: 100-106, 1992.

        4. Gates L: Unpublished data, Universal City Animal Hospital, Universal City, TX, 1997.

        5. Murray J: Unpublished data, Animal Clinic of Farmers Branch, Dallas, TX, 2000.

        6. Eklund CM, Hadlow WJ, Kennedy RC, et al: Aleutian disease of mink: Properties of the etiologic agent and the host responses. J Infect Dis 118:510-516, 1968.

        7. Brandt SJ, Swank RT, Novak EK:The murine Chediak-Hi-gashi mutation and other murine pigmentation mutations, in Gershwin ME, Merchant B (eds): Immunologic Defects in Laboratory Animals, ed 1. New York, Plenum Press, 1981, pp 99-1 17.

        8. Porter DD: Aleutian disease: A persistent parvovirusinfection of mink with a maximal but ineffective host humora1 immune response. Prog Med. Virol 33:42-60, 1986.

        9. Hadlow WJ, Race RE, Kennedy RC: Comparative pathogenicity of four strains of Aleutian disease virus for pas-tel and sapphire.mink. Infret Immun 41:1016-1023, 1983.

        10. Hadlow.WJ, Race RE, Kennedy RC: Royal pastel mink respond variously to inoculation with Aleutian disease virus of low virulence. J Virol 50:38-41, 1984. 11. Hartsough GR, Gorham JR.~ Aleutian disease in mink Natl Fur News 28:10-11, 1956.


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