Treatment Study

Rituxin

Data based on 644 patient profiles

 

11 patients indicated they took Rituxin treatment as their first series or second series if their first series was Watchful Waiting (3).  For this entire group the average response time was 0.75 years and the median response time was 0.7 years.  The average age of this group was 53.6 years and the median age was 52.0 years.  There dose not seem to be any correlation between age and response time.  The age span was from 35 to 69.

 

1 out of the 11 have indicated they have taken a second series of treatment.  The response time for this patient was 1.00 years.

 

10 patients indicated no other treatment at the time they sent in their profile. The average response time for this group was 0.7 years and the median response time was 0.7 years.  If and when profiles are updated with more recent information these numbers need to be recalculated.

 

8 patients indicated they took a combination treatment with Rituxin.   The average response time for this group was 0.8 years and the median response time was 0.8 years.  None of this group has had a second series of treatment.

 

Please note the data supplied by patients were ranges not absolute numbers.  For this study the average of the range given were used in calculating the following information.  These numbers should only be used to show trends.

 

There is not enough data (patients) to calculate Blood test averages and median values.

 

Definitions of terms:

 

Average:  Add all the values in a set numbers and then divide that sum by total of numbers in the set.

 

Median:  The value in the center of a set of values.

 

Response time:  Is from the start of a series of treatment to the start of the next series of treatment.

 

Series:  A set number of courses of a drug.  This is followed by an undetermined time period not requiring treatment. For example: 3 Courses of 2CdA over a 6 month period (this is one series) or some quantity of Cytoxan daily/weekly over two years (this is also one series).  

 

Patient Data

 

_______________ indicates patient was on Watchful Waiting before taking their first series of 2CdA.

 

_______________ indicates patient took a second series of treatment

 

_______________ indicates patient took a combination treatment with 2CdA.

 

 

Id

Private

Age series1

Series

Treatment

Date from

Date to

Response

 Time

Response time

Response time (ongoing)

3

No

58.96

2

Rituxin

7/1/1999

8/1/1999

 

0.66

0.66

98

No

50.61

2

Rituxin

Fludarabine (a nucleoside analogue)

Cytoxan (an alkylating agent)

3/1/1999

3/1/2000

 

0.93

0.93

177

No

50.98

1

Rituxin

10/1/1999

11/1/1999

 

0.36

0.36

179

No

57.88

1

Rituxin

Fludarabine (a nucleoside analogue)

6/1/1999

1/1/2000

 

0.70

0.70

304

No

69.48

1

Rituxin

2Cda (a nucleoside analogue)

Cytoxan (an alkylating agent)

6/22/1999

7/13/1999

 

0.67

0.67

410

No

58.47

1

Rituxin

Fludarabine (a nucleoside analogue)

4/12/1999

10/1/1999

 

0.91

0.91

458

No

35.90

2

Rituxin

2Cda (a nucleoside analogue)

Cytoxan (an alkylating agent)

11/1/1998

1/1/1999

 

1.38

1.38

508

No

65.42

1

Rituxin

8/1/1999

9/1/1999

 

0.66

0.66

575

No

52.05

1

Rituxin

2Cda (a nucleoside analogue)

3/1/2000

8/1/2000

 

0.22

0.22

588

No

42.32

1

Rituxin

Fludarabine (a nucleoside analogue) Other (Specify)

10/1/1999

8/1/2000

 

0.71

0.71

590

No

47.56

1

Rituxin

 Vincristine

1/1/1997

 

1.00

1.00

 

 

 

Blood Test Data Treatment Rituxin

_______________ indicates patient was on Watchful Waiting before taking their first series of 2CdA

 

ID

IgM before 1st

IgM after 1st

Series1

.6 Month reduction

IgM before 2nd

IgM

Most

Recent

WBC before 1st

WBC after 1st

Series1

 6 Month reduction

WBC before 2nd

WBC

Most

Recent

RBC before 1st

RBC after 1st

Series1

6

 Month reduction

RBC before 2nd

RBC

Most

Recent

HBC before 1st

HGB after 1st

Series1

6

Month reduction

HGB

 Before

 2nd

HGB

Most

Recent

177

3749.5

 

 

 

2749.5

2.7

 

 

 

3.2

2.7

 

 

 

3.2

7.7

 

 

 

9.7

179

6749.5

749.5

6000

 

749.5

5.7

3.2

2.5

 

3.2

4.2

4.7

-0.5

 

4.7

12.2

14

-1.8

 

14

304

 

1249.5

 

 

 

 

2.7

 

3.2

 

 

3.7

 

3.2

 

 

12.2

 

13.2

 

410

 

1749.5

 

 

749.5

 

3.2

 

 

3.2

 

3.7

 

 

3.7

 

12.7

 

 

13.2

508

3749.5

4249.5

-500

 

 

7.5

4.2

3.3

 

 

 

4.7

 

 

 

6.7

12.2

-5.5

 

 

575

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

588

3749.5

 

 

 

 

1.7

 

 

 

1.7

2.5

 

 

 

 

8.2

 

 

 

 

590

 

 

 

 

3249.5

 

 

 

 

7.5

 

 

 

 

4.2

 

 

 

 

13.2

3

 

 

 

 

2249.5

 

 

 

 

4.7

 

 

 

 

4.2

 

 

 

 

13.2

98

 

 

 

 

2249.5

 

 

 

 

1.2

 

 

 

 

2.7

 

 

 

 

9.2

458

 

 

 

 

1249.5

 

 

 

 

4.2

 

 

 

 

 

 

 

 

 

14