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Hypothyroidism is common endocrine (glandular) disorder in dogs. In affected dogs, the thyroid gland does not make enough of the thyroid hormones (T3 and T4). These thyroid hormones are necessary to keep many body tissues and organs functioning normally. Thyroid hormones regulate the body's metabolic rate, so hypothyroid dogs are more likely to be sluggish and overweight. However, some cases come on slowly and the signs can easily be missed. Just how common hypothryoidism is in dogs is not known, however, estimates range from 1 in 150 to 1 in 500. Mid- to large-sized dogs seem to be affected more commonly than are small dogs.
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