So, in alphabetical order...
Bob and Ed, updates have been a bit sporadic lately
Chopping Block, updates have been a bit sporadic lately here too.
Ctrl-Altl-Del, I don't think more needs to be said
GU Comics, single pane comedy on a fairly regular basis
Irritability, this links direct to the comic page, but theres other stuff on this site
Little Gamers, Swedish web comic, some straight talking stuff here
Megatokyo, an incredible story, well worth staring from the beginning.
PVP online, based at a game magazine, though they rarely seem to get anything done.
Real Life, loosely based on the artist's own life
(see episodes including spaceships for definition of "loosely")
Light hearted take on the sleazier side of life.
Too Much Information, to prove there is such a thing as TMI.
Turn Signals on a Land Raider, based on the games workshop hobby, very funny.
WTF Comics, another good story comic worth starting at the start
(originally this page had lots of referenced images and different comics, some have vanished and most of the pictures arent there anymore, i've left up the ones that are)
PS. if any of these don't work please mail me.