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| DENTAL NEWS ARCHIVES 032 | 
| New toothpaste cures gum diseaseMay 23, 2000
             LOS ANGELES (Reuters Health) - A chemical used to clear odors 
            from municipal water supplies is the active ingredient in a new 
            toothpaste that cures the bleeding gums of people with gum disease.
             "It kills all bacteria within a minute, and all odors within a 
            few minutes. It's one of the fastest odor neutralizers known," Dr. 
            Howard Alliger of Frontier Pharmaceuticals in Farmingdale, New York, 
            told Reuters Health. "It's phenomenal on gingivitis, curing it in a 
            week if you brush twice a day." 
             
            
             Gingivitis, or gum disease, is caused by bacteria that live in 
            the mouth. The active ingredient in the toothpaste, chlorine 
            dioxide, kills the bacteria by breaking its cell wall. Humans don't 
            have cell walls, Alliger pointed out.
             In a presentation here Monday at the annual meeting of the 
            American Society for Microbiology, he said that laboratory tests 
            showed that the toothpaste killed 99.999% of the microorganisms they 
            tested, including yeast, bacteria, and viruses, within a minute.
             The researchers then had people with gum disease brush their 
            teeth with either their toothpaste or Colgate's Total and found that 
            only their toothpaste stopped the bleeding caused by the gum 
disease.
             The toothpaste is being marketed under the name DioxiBrite, which 
            is only available on Frontier Pharmaceutical's web site 
            (www.frontierpharm.com). "We're developers and researchers, but we 
            don't sell it that well," Alliger admitted. "We're looking for 
            someone to license it or sell it."
             He added that they also have a mouthwash containing chlorine 
            dioxide, and that the chemical also helps heal wounds and scratches, 
            including acne and warts. | 
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