Dexamethsone induced diabetes & hepatic steatosis, a model to screen insulin sensitisers in albino rats, has been developed for the first time by Dr Nagendra Nayak, Professor of Pharmacology, K S Hegde Medical Academy, Deralakatte, Mangalore, India. Screening work has been done using glibenclamide, insulin, metformin, rosiglitazone. Water extracts of Eugenia Jambolana seed, Gymnema sylvestre leaf, Enicostemma littorale & cinnamon  have shown positive reults & Momordica charantia, casearia esculenta, giloy satva  have shown negative reults for insulin sensitising activity. For details contact. Dr Nagendra Nayak, Phone: 91 824 2244425 email: imnnayak@rediffmail.com

Contents

Introduction

Dexamethasone induced diabetes, a model to screen insulin sensitisers?

Dexamethasone induced hepatic steatosis & tinospora cordifolia

Momordica charantia (bitter gourd)

Eugenia Jambolana seed powder

cinnamon