Jacob Harper  b. 16 NOV 1791
married  Jemima Rose  b. 1797,
both born in KY, but there children were born in IN

Charles Rose 1824
Mathias R.  1826
Eliza Ann  1829
SaraH E. 1830
Martin Lea  1837
Malinda Caroline  1838
Alonzo Drake  1838
-------------------------------



Then we have an Indiana Source Book III
(from State Library) showing
Knox Co., Indiana.
marriage licenses & certificates:

Harper, Henry - Eliza Hadden  12-6-1825
Harper, Jacob - Jemima Rose  11-20-1817
Harper, James - Margrette Curry  12-4-1812
Harper, John T. - Caty Glass  2-2-1830
Harper, Joseph - Martha Palmer  11-9-1830
Harper, Thomas - Polly Sullinger  4-2-1821
Harper, William - Elizabeth Dunn  1-29-1813

This info may not help, but maybe the marriages will help another HARPER who is researching. This came from Doug Harper's files, that he so freely shared with me.
MORE ABOUT JACOB
AND HIS SON 
CHARLES ROSE HARPER:
Charles Rose HARPER b. 1824 in Knox Co., IN (d. 1889)
He married
Susan Bain  b. Sept.1837 in Oldham Co., KY (d. 1905)

"Charles Rose HARPER married Susan BAIN in October 1856 in Trimble county. Charles was a physician. Tradition has it that he was highly educated in Europe, and spoke 8 languages fluently." quote by Sara Harper

**
A Time-Line (of Charles R. Harper) below by D. Harper

1856 They married in Bedford, Trimble Co., KY
1857 moved to Louisiana in 1857 where
Charles Lee Harper was born in Desoto Parish, LA
1858 We find Charles and family in Texas (that Spring)
1860 Tifford Edward Harper was born Quitman, Wood Co., Texas
1862 Sidney Randolph Harper was born
1865 Minnie Rose was born in Fannin Co., TX
1868 Matthew drake Harper was born in TX
1870 Adair Co., Missouri: Alonzo Llewellan Harper, b.18 Aug)
1873 Maud Vere Harper was born. (4 April) LaPlata, Macon, Missouri
1876 Back in Texas again
1877 Ella Pearl Harper was born (JAN 29)
1880 Fannin Co., Texas (Charles Lee was not there)
1887 * Minnie Rose married Jeff Faulconer (JAN 26)
1888 *Farney, Kaufman Co., TX  Tilford married Sara Jane Briscoe (Jan 01)
1888 *Chales Lee marries Frances R. Gause (Sept 30) in Hunt Co., TX
1889 Farney, Kaufman Co., TX (Charles died)
1890 Maud married Albert Booth Dellis  (Dec 1890) in Limestone Co., TX
Thank you Doug Harper
for sharing this research