| Human | |
| I-domain | No |
| N-glycos. sites | 14 |
| Conserved cysteines | 18 |
| Total cysteines | 20 |
| Pred. mw from sequence | 110 |
| size (non reduced) | 155 |
| Size (reduced) | 135 + 20 |
| Metal binding sites | 4 |
| Number of aa | 1008 |
| Number of aa cyto domain | 28 |
| Size mRNA | 4,9 |
| Chromosome | 12q11-q13 |
The alpha-5 subunit is also known as CD49e. For this integrin subunit, there's also a knock out mouse available. Mice lacking this subunit show embrionic lethality and mesodermal abnormalities ( Yang et al., 1993. Development 119, 1093-1105 ).
| Alpha-5 human | KLGFFKRSLPYGTAMEKAQLKPPATSDA |
| Accession # | Description | Reference |
| X15203 | Mouse alpha-5 mRNA. | Holers et al., 1989. J. Exp. Med. 169, 1589-1605 |
| X79003 | Mouse alpha-5 mRNA | Morrisey et al., 1994. Unpublished |
| U12683 | Xenopus alpha-5 mRNA. Complete coding sequence | Joos et al., 1995. Mech. Dev. 50, 187-199 |
| X06256 | Human alpha-5 mRNA. | Argraves et al., 1987. J. Cell Biol. 105, 1183-1190 |
Antibody's against the Alpha-5 subunit
| Name | Against | Species | Type | Reference | Com. |
| Sam-1 | Alpha-5 | Mouse | Mono | Keizer et al., 1987. Eur. J. Immunol. 17, 1317-1322 | Yes |
| A21F7 | Alpha-5 (chicken) | Mouse | Mono | Development. 113, 327-337 | |
| D71E2 | Alpha-5 (chicken) | Mouse | Mono | Development. 113, 327-337 | |
| PB1 | Alpha-5 (hamster) | Mouse | Mono | Science. 228, 1448-1451 | |
| P1D6 | Alpha-5 (Hu) | Mouse | Mono | Wayner et al., 1988. J. Cell. Biology 107, 1881-1891 | Yes |
| CLB-705 | Alpha-5 (Hu) | Mouse | Mono | Reference | Yes |
| JBS5 | Alpha-5 (hu) | Mouse | Mono | Reference | Yes |
| HMalpha5-1 | Alpha-5 (rt/ms) | Hamster | Mono | Reference | Yes |
| 5H10-27 | Alpha-5 (ms) | Rat | Mono | Reference | Yes |
| IIA1 | Alpha-5 (hu) | Mouse | Mono | Reference | Yes |
| VC5 | Alpha-5 (hu) | Mouse | Mono | Reference | Yes |
