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One viewer, giving the summary a careful reading, pointed out some crucial typos which I have corrected, and also brought up some important points which I have partly answered now in the body of the summary, such as: How much alcohol did the subjects get? The same viewer raised a question that I could not answer from the information in the article: “What percentage of the ‘three hours after a bedtime drink’ was spent awake, transitioning to sleep, or in sleep...?” It appears that the authors simply did not attempt to characterize the sleep patterns of these subjects, perhaps because the disruptive nature of their measurement produced frequent arousals. He pointed out quite correctly that the subjects did not have obstructive sleep apnea and may not have had even mild sleep-disordered breathing. The important question from all our point of view would be the effects of such amounts of alcohol on the all-night sleep and breathing of people with diagnosed obstructive sleep apnea. Merely looking at the titles of the 31 references listed for this article, it seems that the majority of studies on alcohol effects have been done in normals, but there were at least three studies which plausibly related to sleep apnea, although only one specified that the subjects had obstructive sleep apnea. All three fell outside the time limit of this year or last year which I have set for my reviews of “recent” articles, but I will list the citations for those who are interested: Taasam VC. Block AJ, Boysen PG, Wynne JW: Alcohol increases sleep apnea and oxygen desaturation in asymptomatic men. American Journal of Medicine, 71:240-245, 1981. Scrima L, Broudy M, Nay KN, Cohn MA: Increased severity of obstructive sleep apnea after bedtime alcohol ingestion: Diagnostic potential and proposed mechanism of action. Sleep 5:318-328, 1982. Mitler MM, Dawson A, Henriksen SJ, Sobers M, Bloom FE: Bedtime ethanol increases resistance of upper airways and produces sleep apneas in asymptomatic snorers. Alcoholism 12:801-805, 1988.
Lastly, the same viewer points out that “Studies have shown that one or two glasses of red wine with the evening meal correlates with a decreased risk of heart disease; by swearing off alcohol in the evening, are people with OSA trading one problem for another?” |
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