Before succumbing to the wounds inflicted upon him by CSM's assassins, Mr. X is able to leave a final message for Agent Mulder leading him to his new informant, Marita Covarubbias. Little is currently known about Marita Covarubbias, also known as UNBlonde, other than the fact that she appears to work for the Syndicate. Her alarming personal involvement with rogue agent, Alex Krycek, has recently been revealed. Marita seemingly was utilizing this relationship in order to rescue the innocent Dmitri, whom Krycek had maliciously infected with the Black Cancer. In the process of returning Dmitri to the Syndicate, Marita contracts the infectuous illness. WMM seeks out Krycek in order to acquire the serum to cure her.
Eps: various

Duplicity has yet to be perfected to the art which Alex Krycek lives his life. Assigned as a replacement partner during Agent Scully's abduction, Mulder soon discovered his involvement as a mole for CSM. Fleeing the law, Krycek became a hired hand for the Syndicate... responsible for the theft of FBI evidence, the murders of William Mulder and Melissa Scully, and the assault of Assistant Director Skinner. Ratboy later flees from the Syndicate and sells secrets from the DAT tape to support himself. Mulder soon discovers that Krycek is a high level Russian spy sent by that government to infiltrate the Syndicate and glean their secrets. Krycek recently smuggled a boy,whom he infected with the Black Cancer, and the Russian serum back to the States in order to barter asylum from the Syndicate. Due to the intervention of the WMM, Krycek is seemingly once again working for that secret group.
Eps: various

The "Queen-piece" on the Syndicate's chess board, Cigarette-Smoking Man is always found in those places the Syndicate most needs an agent. Recently, CSM's personal schemes came crashing down on him as the Gethesmane plot threatened to martyrize Agent Mulder. For reasons of his own, CSM attempted to lead Mulder to safety. The First Elder, learning of his deception, sends the Syndicate assassin, Quiet Willy, to terminate him. Gravely injured by the assassin's bullet, Cigarette-Smoking Man retreats to Canada to recover.
Eps: various

Forever seeking the truth behind his sister's disappearance, Agent Mulder receives assistance from a most unlikely source, the Cigarette-Smoking Man. Arranging a meeting in a public place, the CSM brings his "daughter" to meet with Fox. Shocked and disbelieving, Mulder is able to speak with Samantha for a short time before she becomes frightened and returns to her waiting "father" to be returned to her unnamed hiding place. Agent Mulder is left with more questions than ever before, with little hope of ever learning the truth. Is this really Samantha, being foremost coming to mind.
Eps: various

A high-powered Syndicate member that oversees and controls the movements of the Cigarette-Smoking Man and other projects. The Fatman, or First Elder, commands instant respect and immediate attention from the other members of the secret group. Though this member's personal reasons for assisting the Syndicate are as yet unknown, he has, nonetheless, taken steps to eliminate many problems. The Fatman was responsible for assigning Quiet Willy, a Syndicate assassin, to eliminate CSM. Though he failed, The Fatman continues to control the hierarchy of the Syndicate with an iron fist.
Eps: various

Mulder and Scully encounter the mysterious Jeremiah Smith while investigating a hostage situation. Jeremiah is captured by the Syndicate and forced to use his alien healing ability to cure Cigarette-Smoking Man before being allowed to escape. Scully discovers that the Smiths, working for the Social Security Administration, were keeping secret databases on the population. After eluding the Bounty Hunter, Mulder and Smith retreat to Canada, where Jeremiah reveals one of the Syndicate's greatest secrets. After again escaping the Bounty Hunter at the farm, the elusive Smith disappears.
Eps: Talithi Cumi (3X24), Herrenvolk (4X01)

The Alien Bounty Hunter's main purpose is to seek out clones and eliminate them. It is unclear if he is merely a tool of the Syndicate or working under a higher power. He has had numerous encounters with Agents Mulder and Scully, including one wherein he was nearly destroyed by the same weapon he brandishes against the clones. The Bounty Hunter is a lethal killer that never gives up once he has been given a target. His current status is unknown following his recent confrontation with the Alien Rebels.
Eps: various