ALL THE REST –    February 21
  

Today's Quotations — ADVICE
 


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No man is so foolish but he may sometimes give another good counsel, and no man so wise that he may not easily err if he takes no other counsel than his own. He that is taught only by himself has a fool for a master.

— Ben Johnson

One cool judgment is worth a thousand hasty councils. The thing is to supply light and not heat.

Woodrow Wilson

 

 
 


I have lived some thirty years on this planet and I have yet to hear the first syllable of valuable or even earnest advice from my seniors.

— Henry David Thoreau

A word to the wise ain't necessary – it's the stupid ones that need the advice.

Bill Cosby

 

Some people like my advice so much that they frame it upon the wall instead of using it.

Gordon R. Dickson 

 

word puzzleToday's Word – AMENABLE

 



a·me·na·ble
adjective 1. Responsive to advice, authority, or suggestion; tractable.   Synonym obedient. 2. Responsible to higher authority; accountable.  Synonym at responsible. 3. Open to testing, criticism, or judgment. [Probably alteration of Middle English menable, from Old French, from mener, to lead, from Latin min³re³re, to drive, from min³rº, to threaten, from minae, threats.]


"Prithee, friend, leave me alone with my patient," said the practitioner. "Trust me, good jailer, you shall briefly have peace in your house; and, I promise you, Mistress Prynne shall hereafter be more amenable to just authority than you may have found her heretofore.

The Scarlet Letter
Nathaniel Hawthorne


Definitions from American Heritage Dictionary

 

Today's Fact

Over the next several days the facts here on the DM will be about Serendipitous Discoveries.
This is the first fact on this subject.

   

Serendipity
Discoveries

Tranquilizers

 

 
   
 
Serendipity, or chance discovery. This has been the means of a number  of scientific discoveries both great and small. 

 

 
SERENDIPITY 6

  Thorazine - Chlorpromazine, was the first tranquilizer. It was released in the early 1950's. The term 'tranquilizer' was used much before that time. Dr. Benjamin Rush, an early pioneer in the mental health field and a signer of the Declaration of Independence, invented a restraining chair. He named this chair 'the tranquilizing chair.' This device was fitted with a pulley and rope system. The extremely agitated client would be seated in the chair and restrained. The chair would then be raised off the ground and rocked back and forth until the client was quieted. This name, tranquilizer, was then used some 200 years later for drugs that produced a physiologically similar effect as the tranquilizing chair.

In all areas of medicine serendipity has played a major role in discovery and development of drugs and treatments. The area of psychotropic medications has been no exception to this phenomonim. In 1949 Australian physician John Cade observed that lithium had a calming effect on animals. His observation led him to go a step further and try lithium on manic human clients. Some ten years later Cade's findings led to the effacy of lithium in treating manic agitation in humans.

The discovery of the phenothiazine derivatives was a serendipitous laboratory discovery in in the early 1950's in France. This class of drugs was discovered by a chance observation by Laborit that occurred while doing research in the area of antihistamines. Laborit had hoped that the antihistamine research would lead to a new anesthetic. Instead it was discovered that this new substance, Chlorpromazine, had a significant tranquilizing effect. Chlorpromazine Hydrochloride was then tested on schizophrenic clients in 1952. It was introduced in the United states in 1954 and quickly became the drug of choice in treating schizophrenia. By 1970, 85% of all institutionalized psychiatric clients were receiving either chlorpromazine or some other phenothiazine drugs.


A great number of new drugs have been added to this class of drugs over the years. Newer phenothiazine derivatives with fewer side effects and quicker elimination from the body have been developed. Today phenothiazine derivatives are not the only antipsychotic or neuroleptic drugs, but they still compromise nearly two-thirds of all these drugs.

Monoamine oxidase (MAO) inhibitors were also discovered from a chance happening in the 1950's. Isoniazid was a medication used at that time in the treatment of tuberculosis. Early investigators observed that tuberculosis patients became less depressed and demonstrated mood elevation during extended stays in the tuberculosis sanatoria. Some clients even experienced manic behavior to the antituberculosis medication. These observations along with the acknowledgement that the medication inhibited the enzyme monoamine oxidase led to the correlation between brain chemistry and mood. A compound named Iproniazid was developed for uses as a mood elevator. It very closely resembled the antituberculosis drug Isoniazid.

Chlordiazepoxide (Librium) was introduced in 1961. This was the first drug in a new class of psychotropic medicines called the benzodiazepines. This class of drugs resulted from more than 50 years of testing and synthesis of numerous barbiturates.

Sources: Encyclopaedia Britannica | The New Shell Book of Firsts

 

 



This spot is from Kit or Mrs. B stationary. If you use Outlook express as your E-Mail program you might use 'stationary.' Some of the finest stationary that I have seen is available 'free' from Kit and Mrs. B stationary. I have a link to their sites following this thought.

 

DO GOOD ANYWAY

People are often unreasonable, illogical, and self-centered...
Forgive them anyway.

If you are kind, people may accuse you of selfish, ulterior motives...
Be kind anyway.

If you are successful, you will win some false friends and some true enemies...
Succeed anyway.

If you are honest and frank, people may cheat you...
Be honest and frank anyway.

What you spend years building, someone could destroy overnight...
Build anyway.

If you find serenity and happiness, they may be jealous...
Be happy anyway.

The good you do today, people will often forget tomorrow...
Do good anyway.

Give the world the best you have, and it may never be enough...
Give the world the best you've got anyway.

You see, in the final analysis, it is between you and God...
It never was between you and them anyway.


Kit http://www.kitwhite.com

Mrs. B http://www.mrandmrsb.com

 

clown
Today's SMILE

 

 

"What sunshine is to flowers, smiles are to humanity. These are but trifles, to be sure; but, scattered along life's pathway, the good they do is inconceivable."

Joseph Addison

 

A cheerful heart is good medicine,
but a crushed spirit dries up the bones.
Proverbs 17:22 (NIV)

 
   

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Things Learned From KIDS


The Home Physics Laboratory

Frogs can survive the washing machine but don't do well in the dryer. Frog bits will never come out of dried clothes. Throw them away before they stink up the whole house.

Ditto snakes.

Mascara on cat whiskers makes really cool wavey lines on anything onto which he tries to rub it off. They do not come off of paint.

Boys can jump off a two story high roof and break nothing but mom will be on tranquilizers for at least a week.

If you stick a lighter into the sprinkler head in the bathroom, the sprinklers will go off in the entire loft. It takes 5 minutes to raise the level of water to the point where the downstairs neighbor is also getting flooded.

Long-haired dogs hate Epilady.

David in Sunnyvale, California VIA – H u m o u r N e t



Good Deed For the Day

A guy is at the Pearly Gates, hoping to be admitted, and St. Peter says to the guy, "I can't see that you did anything really good in your life, but you never did anything bad either. I tell you what: if you can tell me one REALLY good deed that you did, you're in."

So the guy says, "Once I was driving down the road and saw a gang of bikers assaulting this poor girl. So I pulled over, got out my car, grabbed a tire iron and walked straight up to the gang's leader -- a huge ugly guy with a studded leather jacket, bald head but with hair
all over his body, and a chain running from his nose to his ear.

"Undaunted, I ripped the chain out of his nose and ear and smashed him over the head with the tire iron. Then I turned around and, wielding my tire iron, yelled to the rest of them, 'You leave this poor, innocent lady alone! You're all a bunch of sick, deranged
animals! GO HOME BEFORE I TEACH YOU ALL A LESSON IN PAIN!'"

Impressed, St. Peter says, "Really? When did this happen?"

"Oh, about two minutes ago."


Code of Ethical Patient Behavior


1.DO NOT EXPECT YOUR DOCTOR TO SHARE YOUR DISCOMFORT
Involvement with the patient's suffering might cause him to lose valuable scientific objectivity.

2.BE CHEERFUL AT ALL TIMES
Your doctor leads a busy and trying life and requires all the gentleness and reassurance he can get.

3.TRY TO SUFFER FROM THE DISEASE FOR WHICH YOU ARE BEING TREATED
Remember that your doctor has a professional reputation to uphold.

4.DO NOT COMPLAIN IF THE TREATMENT FAILS TO BRING RELIEF
You must believe that your doctor has achieved a deep insight into the true nature of your illness, which transcends any mere permanent disability you may have experienced.

5.NEVER ASK YOUR DOCTOR TO EXPLAIN WHAT HE IS DOING OR WHY HE IS DOING IT
It is presumptuous to assume that such profound matters could be explained  in terms that you would understand.

6.SUBMIT TO NOVEL EXPERIMENTAL TREATMENT READILY
Though the surgery may not benefit you directly, the resulting research paper will surely be of widespread interest.

7.PAY YOUR MEDICAL BILLS PROMPTLY AND WILLINGLY
You should consider it a privilege to contribute, however modestly, to the well-being of physicians and other humanitarians.

8.DO NOT SUFFER FROM AILMENTS THAT YOU CANNOT AFFORD
It is sheer arrogance to contract illnesses that are beyond your means.

9.NEVER REVEAL ANY OF THE SHORTCOMINGS THAT HAVE COME TO LIGHT IN THE COURSE OF TREATMENT BY YOUR DOCTOR
The patient-doctor relationship is a privileged one, and you have a sacred duty to protect him from exposure.

10.NEVER DIE WHILE IN YOUR DOCTOR'S PRESENCE OR UNDER HIS DIRECT CARE
This will only cause him needless inconvenience and embarrassment.


A guy calls...

A guy calls the hospital. He says, "You gotta send help! My wife's going into labor!"

The nurse says, "Calm down. Is this her first child?"

He says, "No! This is her husband!"   

KashaL@concentric.net   | Kasha Linka


Which way?!?

A man is doing his first skydive. He jumps from the plane, freefalls for a bit, then pulls his main rip-cord... nothing happens.  After a short panic, he pulls his reserve rip-cord... again, nothing happens! As he's zooming toward the ground, another man comes shooting past him TOWARDS THE SKY! The jumper hollers, "Hey! Do you know anything about rip-cords???"

The other man returns, "NOooooo! Do you know anything about gas stoves?"

KashaL@concentric.net   | Kasha Linka



TRUE FACT ...

Humans begin laughing at two to three months of age. Six year olds laugh about 300 times per day, while adults laugh from 15 to 100 times per day.

SOURCE: NYT, Dr. William F. Fry, Stanford University

 

smile

 


If you're feeling good, don't worry. You'll get over it.

 

 


Daily Miscellany Comics

 

Have A Great Day

Phillip Bower

 

Soul Food - devotions, Bible verse and inspiration.

Soul Food February 21

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Today in History February 21

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Copyright Information: Phillip Bower is not the author of the humor, and does not claim to own any copyright privileges to the jokes. Sources of jokes are listed when known. Birthday's and Happenings for the date, and quotations are public knowledge and collected from numerous sources. Quotations are public knowledge and sources are listed when known. Weekendspirations are written by Tim Knappenberger who has copyright privileges. Cathy Vinson authors Whispers from the Wilderness and owns copyright privileges. Weekendspirations and Whispers from the Wilderness are used with permission by the respective authors. Other devotions are written by Phillip Bower unless otherwise stated. In all cases credit is given when known. The Daily Miscellany is nonprofit. Submissions by readers is welcome.