Alpha-1 integrin subunit

Factsheet

Rat
I-domainYes
N-glycos. sites24
Conserved cysteines17
Total cysteines23
Pred. mw from sequence127,8
size (non reduced)200
Size (reduced)210
Metal binding sites3
Number of aa1152
Number of aa cyto domain15
Size mRNA11
Chromosome5 (human)

The alpha-1 subunit is also known as CD49a. For this integrin subunit, there's also a knockout mouse available. These mice however do not show any abnormal phenotype( Gardner et al., 1996. Dev. biol. 301, 301-313 ).

Amino acid sequences of cytoplasmic domain

Alpha-1 ratKIGFFKRPLKKKMEK
Alpha-1 human KIGFFKRPLKKKMEK

Antibody's against alpha-1 subunit
Name Against Species Type Reference Com.
TS2/7Alpha-1 (hu) Mouse Mono Reference Yes
Ha31/8 Alpha-1 (rt/ms) Hamster Mono Reference Yes

Last updated on 18/06/97

© 1997 jkoster@hotmail.com

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