Alpha-2 integrin subunit

Factsheet

Human
I-domainYes
N-glycos. sites10
Conserved cysteines17
Total cysteines20
Pred. mw from sequence126
size (non reduced)160
Size (reduced)165
Metal binding sites3
Number of aa1152
Number of aa cyto domain27
Size mRNA8
Chromosome5

The alpha-2 subunit is also known as CD49b.

Amino acid sequences of cytoplasmic domain
Alpha-2 human KLGFFKRKYEKMTKNPDEIDETTELSS

Genbank sequences (EMBL) which exist for this integrin subunit
Accession # Description Reference
M28249 Human alpha-2 (vla-2) Takada et al., 1989. J. Cell Biol. 109, 397-407
L43058 Xenopus alpha-2. Partial Meng et al. Unpublished

Antibody's against the Alpha 2 subunit
Name Against Species Type Reference Com.
P1E6 Alpha-2 (human) Mouse Mono Wayner and Carter, 1987. J. Cell. Biol. 105, 1873-1884
P1H5 Alpha-2 (human) Mouse Mono Wayner and Carter, 1987. J. Cell. Biol. 105, 1873-1884
10G11 Alpha-2 (human) Mouse Mono Reference
P1H6 Alpha-2 (human) Mouse Mono Reference
5E8 Alpha-2 Species Mono Chen et al., 1991. J. Exp. Med. 173, 1111-
12F1 Alpha-2 Species Mono Pischel et al., 1987. J. Immunol. 138, 226-
RX2 Alpha-2 (human) Rabbit Poly Takada et al., 1989. J. Cell. Biol. 109, 397-407
JBS2Alpha-2 (hu) Mouse Mono Reference Yes
AK-7Alpha-2 (hu) Mouse Mono Reference Yes
16B4Alpha-2 (hu) Mouse Mono Reference Yes
31H4Alpha-2 (hu) Mouse Mono Reference Yes
Ha1/29 Alpha-2 (rt) Hamster Mono Reference Yes
HMalpha2 Alpha-2 (ms) Hamster Mono Reference Yes
12F-H6 Alpha-2 (hu) Mouse Mono Reference Yes

Last updated on 03/10/97

© 1997 jkoster@hotmail.com


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