Alpha-M integrin subunit

Factsheet

Human
I-domainYes
N-glycos. sites19
Conserved cysteines19
Total cysteines22
Pred. mw from sequence125,6
size (non reduced)-
Size (reduced)170
Metal binding sites3
Number of aa1137
Number of aa cyto domain24
Size mRNA4,7
Chromosome16p11-p13,1

The alpha-M subunit is also known as CD11b.

Amino acid sequences of cytoplasmic domain

Human Alpha-M KLGFFKRQYKDMMSEGGPPGAEPQ
Mouse Alpha-M KLGFFKRQYKDMMNEAAPQDAPPQ

Genbank sequences (EMBL) which exist for this integrin subunit
Accession # Description Reference

Antibody's against the alpha-M subunit
Name Against Species Type Reference Com.
LM2/1 Alpha-M (hu) Mouse Mono Reference Yes
MRC OX-42 Alpha-M (rt) Mouse Mono Reference Yes
5C6 Alpha-M (ms) Rat Mono Reference Yes
H5A4 alpha-M (human) mouse mono reference
LM2/1.6.11 alpha-M (human) mouse mono J. Immunol 137, 2891-2900
M1/70.15.11.5.2 Alpha-M (mouse) Rat Mono Eur. J. Immunol. 8, 539-551 Yes
44Alpha-M (hu) Mouse Mono Reference Yes
WT.5 Alpha-M (rt) Mouse Mono Reference Yes

Last updated on 18/06/97

© 1997 jkoster@hotmail.com


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