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DECODING SCHEME IN THE MOLECULE OF INSULIN (3) C o de 139 Molecule of insulinChain A Phe,(F), Val(V), Asn(N), Gln(Q), His(H), Leu(L), Cys(C), Gly(G), Ser(S), His(H), Leu(L), Val(V), Glu(E), Ala(A), Leu(L), Tyr(Y), Leu(L), Val(V), Cys(C), Gly(G), Glu(E), Arg(R), Gly(G), Phe(F), Phe(F), Tyr(Y), Thr(T), Pro((P), Lys(K), Ala(A) Chain B Glu(E), Ileu(J), Val(V), Glu(E), Gln(Q), Cys(C), Cys(C), Ala(A), Ser(S), Val(V), Cys(C), Ser(S), Leu(L), Tyr(Y), Gln(Q), Leu(L), Glu(E), Asn(N), Tyr(Y), Cys(C), Asn(N), Number of atoms: Chain A F=23; V=19; N=17, Q=20; H=20; L=22; C=14; G=10; S=14; H=20; L=22; V=19; E=19; A=13; L=22; Y=23; L=22; V=19; C=14; G=10; E=19; R=25; G=10; F=23; F=23; Y=23; T=17; P=17; K=24; A=13; = 556 atoms. Chain B E=19; J=22; V=19; E=19; Q=20; C=14; C=14; A=13; S=14; V=19;C=14; S=14; L=22; Y=23; Q=20; L=22; E=19; N=17; Y=23; C=14; N= 17;=378 atoms Decoding formula:139½ ½ 931[ S7(X1) + S7(X2)] = 931; (X1 + X2) = 139; 139½ ½ 931X1 and X2 = Number of atoms in groups of aminoacids X1 and X2; Chain “A” Example 1 X1 = (Tyr(Y), Leu (L), Val(V), Cys(C) and Gly(G) = ( 23 atoms + 22 atoms + 19 atoms + 14 atoms + 10 atoms) = 88 atoms;X2 = Val(V), Cys(C), Gly(G) and Glu(E) = Gly(G), Pro(P) andLys(K) = ( 10 atoms + 17 atoms + 24 atoms) = 51 atoms; [ S7(X1) + S7(X2) = 931; [ S7(88) + S7(51) = 931; S7(88) = (82+83+84+85+86+87+88) = 595; S7(51) = (45+46+47+48+49+50+51) = 336; (595 + 336) = 931; ………………. Example 2 X1 = (Phe(F), Val(V), Asn(N) = ( 23 atoms + 19 atoms + 17 atoms) = 59 atoms; X2 = His(H), Leu(L), Cys(C) and Lys(K) = ( 20 atoms + 22 atoms + 14 atoms + 24 atoms ) = 80 atoms; [ S7(X1) + S7(X2) = 931; [ S7(59) + S7(80) = 931; S7(59) = (53+54+55+56+57+58+59) = 392; S7(80) = (74+75+76+77+78+79+80) = 539; (392 + 539) = 931; ………………. Example 3 X1 = (Leu(L), Cys(C), GlyG) = ( 22 atoms + 14 atoms + 10 atoms) = 46 atoms; X2 = Val(V), Cys(C), Gly(G), Gly(G), Gly(G), Pro(P) and Ala(A) = ( 19 atoms + 14 atoms + 10 atoms + 10 atoms + 10 atoms + 17 atoms + 13 atoms ) = 93 atoms; [ S7(X1) + S7(X2) = 931; [ S7(46) + S7(93) = 931; S7(46) = (40+41+42+43+44+45+46) = 301; S7(93) = (87+88+89+90+91+92+93) = 630; (301 + 630) = 931; ………………. Example 4 X1 = Leu(L), Val(V) and Cys(C) = 22 atoms + 19 atoms + 14 atoms) = 55 atoms; X2 = Val(V), Glu(E), Ala(A), Tyr(Y) and Gly (G) = ( 19 atoms + 19 atoms + 13 atoms + 23 atoms + 10 atoms) = 84 atoms; [ S7(X1) + S7(X2) = 931; [ S7(55) + S7(84) = 931; S7(55) = (49+50+51+52+53+54+55) = 364; S7(84) = (78+79+80+81+82+83+84) = 567; (364 + 567) = 931; ………………. Etc. Chain "B" Example 1 X1 = Glu(E), Ileu (I) and Val(V) = ( 19 atoms + 22 atoms + 19 atoms) = 60 atoms;X2 = Ser(S), Leu(L), Tyr(Y) and Gln(Q) = =( 14 atoms + 22 atoms + 23 atoms + 20 atoms) = 79 atoms; [ S7(X1) + S7(X2) = 931; [ S7(60) + S7(79) = 931; S7(60) = (54+55+56+57+58+59+60) = 399; S7(79) = (73+74+75+76+77+78+79) = 532; (399 + 532) = 931; ……… Example 2 X1 = Ala(A), Ser(S), Val(V), Cys(C) = ( 13 atoms + 14 atoms + 19 atoms + 14 atoms) = 60 atoms; X2 = Ser(S), Leu(L), Tyr(Y) and Gln(Q) = =( 14 atoms + 22 atoms + 23 atoms + 20 atoms) = 79 atoms; [ S7(X1) + S7(X2) = 931; [ S7(60) + S7(79) = 931; (399 + 532) = 931; ………………. Example 3 X1 = Glu(E), Ileu(I), Val(V), Glu(E) = =( 19 atoms + 22 atoms + 19 atoms + 19 atoms) = 79 atoms; X2 = Ala(A), Ser(S), Val(V), Cys(C) = =( 13 atoms + 14 atoms + 19 atoms + 14 atoms) = 60 atoms; [ S7(X1) + S7(X2) = 931; [ S7(79) + S7(60) = 931; (532 + 399) = 931; ………………. Example 4 X1 = Glu(E), Ileu(I), Val(V), Glu(E) = =( 19 atoms + 22 atoms + 19 atoms + 19 atoms) = 79 atoms; X2 = Cys(C), Ala(A), Ser(S), Val(V), = ( 14 atoms + 13 atoms + 14 atoms + 19 atoms) = 60 atoms; [ S7(X1) + S7(X2) = 931; [ S7(79) + S7(60) = 931; (532 + 399) = 931; ………………. Etc.
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