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Early Ovarian
Cancers Detected at Stage IA by TVS Screening
This table summarizes the
screening program's experience with Stage IA ovarian cancers. All 8 of
the cases below represent a cancer caught by TVS imaging while it was
still early and curable; take special note that 7 of the 8 women were
considered normal on a physical exam, showing that a gynecological visit
alone would not have caught their cancers at such an early stage.
(Cases underlined in blue can be clicked on to access actual TVS images).
|
Case |
A |
B |
C |
D |
E |
F |
G |
H |
|
Age at Dx |
72 |
50 |
42 |
36 |
55 |
66 |
64 |
63 |
|
CA-125, U/ml |
7 |
14 |
14 |
|
|
37 |
|
|
|
Physical Exam |
Normal |
Normal |
Palpable |
Normal |
Normal |
Normal |
Normal |
Normal |
|
TVS size, cm3 |
75 |
19.4 |
14.7 |
32.1 |
14.7 |
39.8 |
25 |
223.1 |
|
TVS – cystic |
+ |
+ |
|
+ |
+ |
|
+ |
+ |
|
TVS – solid |
|
+ |
|
|
|
|
|
|
|
TVS – papillation |
+ |
|
|
|
|
|
|
|
|
TVS – septation |
|
|
|
+ |
+ |
|
+ |
+ |
|
TVS – MI |
5 |
8 |
1 |
5 |
6 |
6 |
3 |
8 |
|
Tumor Stage |
IA |
IA |
IA |
IA |
IA |
IA |
IA |
IA |
|
Treatment |
S |
S & C |
S |
S |
S |
S |
S & C |
S |
|
Status |
A & W |
A & W |
A & W |
A & W |
A & W |
A & W |
A & W |
A & W |
|
DX Date |
Jan-90 |
Aug-90 |
Mar-93 |
Mar-93 |
May-94 |
Jan-95 |
April-96 |
Jul-97 |
|
Years Post Dx |
9.5 |
9.0 |
6.0 |
6.0 |
5.2 |
4.5 |
3.2 |
2.0 |
S = surgery
S & C = surgery + chemotherapy
A & W = alive and well
Dx = diagnosis
|
Case |
Histology (cancer cell
type) |
|
A |
Granulosa cell tumor, Grade
2 |
|
B |
Adenocarcinoma, Grade 3 |
|
C |
Serous cystadenocarcinoma,
Grade 3 |
|
D |
Endometriod carcinoma ,
Grade 1 |
|
E |
Granulosa cell tumor,Grade 2 |
|
F |
Endometriod carcinoma, Grade
2 |
|
G |
Endometriod carcinoma |
|
H |
Borderline serous ovarian
epithithelial Tumor |
|
 |
 |
|