Search for specific topic by selecting first letters:

Tropical sprue

Definition

Tropical sprue is a malabsorption syndrome of unknown cause that is prevalent in the tropics and subtropics.

Causes, incidence, and risk factors

The cause of this disease is unknown, but it may be related to an infectious organism. The condition affects residents of or visitors to the tropics. The main symptom is diarrhea, which may improve on leaving tropical areas, or may reappear years after leaving the tropics. Risk factors are residence in the tropics or prolonged travel to tropical destinations.

Symptoms

In children, sprue most often presents with growth failure and delayed skeletal maturation.

Signs and tests

Treatment

Treatment begins with rehydration with fluids and electrolytes. Replacement of folate, iron, vitamin B12, and others may also be needed. Antibiotic therapy with tetracycline is given at the beginning of treatment.

Oral tetracycline is usually not prescribed for children until after all permanent teeth have erupted. It can permanently discolor teeth that are still forming.

Expectations (prognosis)

The outcome is expected to be good with treatment.

Complications

Vitamin and mineral deficiencies are common complications.

Calling your health care provider

Call your provider if you experience prolonged diarrhea or other symptoms of this disorder, especially after spending time in the tropics.

Call your provider if tropical sprue symptoms worsen or do not improve with treatment, or if new symptoms develop.

Prevention

Other than avoiding living in or traveling to tropical climates, there is no known prevention for tropical sprue.

Illustrations

Digestive system
Digestive system
Digestive system organs
Digestive system organs

Page Content:

sprue tropical; non sprue tropical