Steroid rage
The anabolic effect of testosterone would become increasingly stronger. steroid rage Side effects of steroid use. In reality, untrained people who use steroids have very limited muscle growth. hey rapidly become immune to testosterone's anabolic effect. That doesn't sound like androgen receptor upregulation, does it?"First, no one has claimed that weight training is not needed for the steroid-using bodybuilder. steroid rage Pictures-of-side-effects-of-steroids. This is a strawman argument. Resistance training is demonstrated to upregulate the androgen receptor, for example, and also stimulates growth by other means. Therefore it is not surprising that those who do not train do not gain nearly as much muscle as those who do. steroid rage Steroids for sale perscription. The argument that AAS use alone, without training, will not produce a championship physique proves nothing with respect to how the androgen receptor is regulated. It does not even suggest anything, to any person with judgment. And the concept that upregulation could only exist as an uncontrollable upwards spiral is entirely incorrect. Rather, for any given hormone level, there will be a given AR level. There is no feedback mechanism, not even a postulated one, where this would then lead to yet higher hormone level, leading to yet higher AR level, etc. In fact there is negative feedback, since upregulation of the AR in the hypothalamus and pituitary in response to higher androgen would lead to greater inhibition of LH/FSH production, and therefore some reduction in androgen production. In the case of sedentary subjects, let us use the subjects in the NEJM study, who received 600 mg/week testosterone, as our example. While I do not know if these subjects did experience AR upregulation in their skeletal muscle tissue, if their receptor numbers had let us say increased by some percentage, there would come some point in increased muscle mass where catabolism again matched anabolism, and further growth would not occur. No runaway spiral of muscle growth would be expected either. Thus, my colleague is arguing against non-issues. Lastly, such persons do not, as he claimed, become immune to testosterone's anabolic effect: they maintain the higher muscle mass so long as they are on the drug. "After all, the heaviest steroid users are found among bodybuilders. In those heaviest users there should be upregulation of androgen receptors. If that were true, here's what would happen. The androgens would cause their receptors to multiply and get increasingly more potent as time went on.
Steroid rage
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