Introduction |
Microarray Technology in Diagnosis
Introduction
Microarrays are clinically useful as diagnostic tools. Here, we shall discuss how they have been used in three particular examples. First, as a tool to identify which bacteria is causing meningitis. Second, as a tool in screening a population for an opthalmic disorder. Finally, we shall look at how microarrays serve as a prognostic indicator for different types of cancer in a CML model. To be continued . . .
Liu Y, Han J, Huang H, zhu B. Development and Evaluation of 16S rDNA Microarray for Detecting Bacterial Pathogens in Cerebrospinal Fluid. Exp Biol Med. 2005;230:587-591.
Zernant J, Kulm M, Dharmaraj S, et al. Genotyping Microarray (Disease Chip) for Leber Congenital Amaurosis: Detection of Modifier Alleles. Invest Ophthalmol Vis Sci. 2005;46:3052-3059
Yong ASM, Szydlo RM, Goldman JM, et al. Molecular profiling of CD34+ cells identifies low expression of CD7 with high expression of proteinase 3 or elastase as predictors of longer survival in CML patients. Blood. 2005.
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Experimental Design & Diagnosis | |
Image Processing & Data Analysis | |
Papers | |
MicroArray Program | |
References | |
Nash, S. | |
Aranibar, M. |