1974 Laboratory in Italy: A dog undergoes a series of experiments.

Dog with skin covering the skull excised. An incision was made to expose the cortex of the brain.

Day 6 of a toxicity test, LD 50, lethal dose 50%.

This beagle was convulsing, having great difficulty breathing, and unable to stand.   Discharge and bleeding from the eyes are visible. Over 300,000 beagles were used in toxicity testing in the UK in 1983.

This puppy was given drugs to prevent rejection of a heart transplant. The flesh on the back legs rotted off.

This dog's head is held in a holder for stereotaxic surgery.