Leg muscle pain
The white cell count is usually normal in patients with rheumatoid arthritis, but can be mildly elevated secondary to inflammation. leg muscle pain Ear pain in adults. Similarly, the platelet count is usually normal but thrombocytosis occurs in response to inflammation. Drug reactions and Felty's syndrome are rare causes of leukopenia or thrombocytopenia (see below). The erythrocyte sedimentation rate (ESR) is usually elevated in patients with rheumatoid arthritis and in some patients is a helpful adjunct in following the activity of the disease. leg muscle pain Joint travel regulation. (top of section) Serology Rheumatoid factors are antibodies directed against the Fc portion of immunoglobulin G (IgG). A positive test for rheumatoid factor is by no means pathognomonic of rheumatoid arthritis, but is present in 70 to 90% of patients with the disease. The titer does not correlate with the activity of disease, but patients with a high titer rheumatoid factor are more likely to have erosive joint disease, extra-articular manifestations, and greater functional disability. leg muscle pain Diseases-on-arthritis. In contrast, generally, rheumatoid factor negative patients exhibit a milder disease course. Rheumatoid factors are also detectable in non-rheumatoid patients who have chronic antigenic stimulation, such as prolonged infection (bacterial endocarditis, tuberculosis, cytomegalovirus, human immunodeficiency virus (HIV), collagen vascular disease, or dysproteinemia). Low titers of rheumatoid factors may be detected in the serum of apparently normal people, especially over the age of 70, where its prevalence is anywhere from 10 - 25%. The anti-nuclear antibody (ANA) is positive in 20-30% of patients with rheumatoid arthritis and is more common in patients with extra-articular manifestations. (top of section) Radiology Radiological findings early in the disease may show nothing other than soft tissue swelling. Thereafter, periarticular osteopenia may develop. With progression of their disease, narrowing of the joint space is caused by loss of cartilage, and juxta-articular erosions appear, generally at the point of attachment of the synovium. In end-stage disease, large cystic erosions of bone may be seen.
Leg muscle pain
Neck || Arthritis-in-cats || Thigh-pain || Pain-under-left-rib