Wisconsin State Route 16 runs east-west across Central La Crosse County. This runs in the Interstate 90 corridor. WI St Rt 16 passes through the following towns in La Crosse County. West Salem
WB WI St Rt 16 near Bangor. A BGS on WB I-90. WB WI St Rt 16 near I-90 in Onalaska. WB WI St Rt 16 near La Crosse. A junction maker on WB U.S. Rt. 14/NB U.S. Rt. 61. WB U.S. Rt. 14/NB U.S. Rt. 61/WB WI St Rt 16 in La Crosse. WB U.S. Rt. 14/NB U.S. Rt. 61/WB WI St Rt 16 on the La Crosse side of the Mississippi River Bridge. (June, 2005) Mid span of the Mississippi River Bridge. WB U.S. Rt. 14/NB U.S. Rt. 61/WB WI St Rt 16 on the westside of the birdge. EB U.S. Rt. 14/SB U.S. Rt. 61/EB WI St Rt 16 near the Wisconsin/Minnesota State Line.