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Why Are T Cells Tolerant To Hepatitis B Virus?
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Why Are T Cells Tolerant To Hepatitis B Virus?
Main Category: Liver Disease / Hepatitis
Article Date: 15 Oct 2008 - freeware virus program 2:00 PDT
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The level of PD-1 expression has been proved by recent studies to be positively correlated with the extent of HBV-specific T cell impairments. However, the degree of T cell exhaustion which affects the panda free virus scan disease statuses of hepatitis B patients has so far been only evaluated in restricted and small groups Reviews Of Intego Virus Barrier Software of patients between those cytomegalo virus with established chronicity and subjects with acute virus scanning program HBV infection. Besides, whether levels of PD-1 expression on T cells differ between acute exacerbation of hepatitis B and chronic HBV infected patients is still unknown.
A research article published in the World Journal of Gastroenterology addresses this question. The research team led by Shu-Ling Zhang from Tongji Medical College of Huazhong University of Science and Technology in China examined the expression of PD-1 on antigen specific CD8+ T cells in peripheral blood of chronic hepatitis B (CHB) and acute exacerbation of hepatitis B (AEHB) patients.
They found that the levels of PD-1 on total CD8+ T cells in CHB patients were significantly higher than those in AEHB patients and healthy individuals. Conversely, lower frequencies of HBV-specific CD8+ T cells were detected in samples blood test respiratory virus infants asthma from chronic patients compared to AEHB patients. Our results confirmed reports that HBV specific CD8+ T-cell responses in peripheral blood were intensified in samples from AEHB patients than in those from patients with chronic hepatitis who remains viral persistence. Besides, there was a significant positive correlation between HBV viral load and percentage of PD-1 expression on CD8+ T cells in CHB and AEHB group of subjects. However, PD-1 expression was not in association with disease flare-ups indicator alanine aminotransferase (ALT). This study clarified the correlation between PD-1 expression and two different HBV infection Best Virus Protection Program statuses.
----------------------------
Article adapted by Medical News Today from original press release.
----------------------------
Reference: Ye P, Weng ZH, Zhang SL, Zhang JA, Zhao L, Dong JH, Jie SH, Pang R, Wei RH. PD-1 expression is diseases caused by virus associated with the disease statuses of hepatitis B virus infection. World Microsoft Virus Current J Gastroenterol 2008; 14(28): 4551-4557 http://www.wjgnet.com/1007-9327/14/4551.asp
Correspondence to: Shu-Ling Zhang, Department of hepatology and infectious disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China.
About World Journal of Gastroenterology
World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H pylori infection and provides a forum for both clinicians and scientists. WJG has been indexed and abstracted in Current Contents/Clinical Medicine, Science Citation Index Expanded (also known as SciSearch) and Journal Citation Reports/Science Edition, Index Medicus, MEDLINE and PubMed, Chemical Abstracts, how to remove virus EMBASE/Excerpta Medica, Abstracts Journals, Nature Clinical Practice Gastroenterology and virus cd-drive no system found Hepatology, CAB Abstracts and Global Health. ISI JCR 2003-2000 IF: 3.318, 2.532, 1.445 and 0.993. WJG is a virus repair disk weekly journal published by WJG Press. The publication dates are the 7th, 14th, 21st, and 28th day of every month. WJG is supported by The National Natural Science Foundation of China, No. 30224801 virus olympic torch and No. 30424812, and was founded with the name of China National Journal of New Gastroenterology on October 1, 1995, and renamed WJG on January 25, 1998.
About The WJG Press
The WJG Press mainly publishes World Journal of Gastroenterology.
Source: Lai-Fu Li
World Journal of Gastroenterology
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For any corrections of virus software reviewfactual information, or to contact the editors Removing Virus please use our feedback form. Please send any medical news strange virus causing headaches or health news press remove sites virus releases to: Back to top Back to front page List of All Medical Articles Privacy Policy Terms and Conditions © 2008 MediLexicon International virus and tongue Ltd News Category Menu Liver Disease / Hepatitis > Categories never get a virus again A-B Abortion Acid Reflux / GERD ADHD Aid / Disasters Alcohol / Addiction / Illegal Drugs Allergy Alternative Medicine Alzheimer's / Dementia Anxiety / Stress Arthritis / Rheumatology Asthma Autism Back Pain (NEW) Bio-terrorism / Terrorism Biology / Biochemistry Bipolar Bird Flu / Avian Flu Blood / Hematology Body Aches Bones / Orthopaedics Breast Cancer > Categories C-D Cancer / Oncology Cardiovascular / Cardiology Caregivers / Homecare Cervical Cancer / HPV Vaccine Cholesterol CJD / vCJD / Mad Cow Disease Cleft Palate Clinical Trials / Drug Trials Colorectal Cancer Complementary Free Norton Antivirus Virus Definition Medicine Compliance Conferences Cosmetic Medicine Crohn's Cystic Fibrosis Dentistry Depression Dermatology Diabetes Dyslexia > Categories E-G Ear, Nose and Throat Eating Disorders Eczema / Psoriasis (NEW) Endocrinology Epilepsy Erectile Dysfunction Eye Health / Blindness Fertility Flu / Cold / SARS GastroIntestinal / Gastroenterology Genetics Gout Gynecology > Categories H-L Headache / Migraine Health Insurance / Medical Insurance Hearing / Deafness Heart Disease (NEW) HIV / AIDS Huntingtons Disease Hypertension Immune System / Vaccines Infectious Diseases Irritable-Bowel Syndrome IT / Internet / E-mail Liver Disease / Hepatitis Lung Cancer Lupus Lymphoma / Leukemia > Categories M-O Medical Devices / Diagnostics Medical Malpractice / Litigation Medical Students / Training Medicare / Medicaid / SCHIP Men's health Menopause (NEW) Mental roto virus treatment Health MRI / PET / Ultrasound MRSA / Drug Resistance Multiple Sclerosis Muscular Dystrophy / ALS Neurology / Neuroscience Nursing / Midwifery Nutrition /avir anti virusDiet Obesity / Weight Loss / Fitness Ovarian Cancer (NEW) > Categories P-R Pain / Anesthetics Parkinson's Disease Pediatrics / Children's Health Pharma / Biotech Industry Pharmacy / Pharmacists Plastic Surgery Pregnancy / Obstetrics Premature Ejaculation Primary Care / General Practice Prostate / Prostate Cancer Psychology / Psychiatry Public Health Radiology / Nuclear Medicine Regulatory Affairs / Drug Approvals Rehabilitation / Physical Therapy Respiratory > Categories S-Z Schizophrenia Seniors / Aging Sexual Health / STDs Sleep / Sleep Disorders Smoking / Quit Smoking Sports Medicine / Fitness Statins Stem Cell Research Stroke Transplants / Organ Donations Tropical Diseases Tuberculosis (NEW) Urology / Nephrology Veterinary Viruses / Bacteria Water - Air Quality / Agriculture Women's Health View full category list News Options Customized Homepage Weekly anti virus vista Newsletters Daily News Alerts Navigation Links Home About Us News Licensing Free Website Feeds Free Tools & Content Links Tell a microsoft and anti virus software Friend Accessibility Help / FAQ Article Submission Contact Us Health Professional Sites Psychiatry Urology Patient Information Hubs Bipolar Diabetes Schizophrenia Clinical Trials Latest News For Liver Disease / Hepatitis Consensus Statement On Hepatitis B To Be Released By NIH Oct. 22 15 Oct 2008 Why Are T Cells Tolerant To Hepatitis B Virus? 15 Oct 2008 Resveratrol false virus warnings Prevents Fat Accumulation In clamoxa and herpes virus Livers Of 'Alcoholic' cell phone virus Mice 14 Oct 2008 View more news... Latest Videos for Liver Disease Hepatitis C Overview Hepatitis C is called a silent epidemic because many people are unaware they carry this virus of the liver. But experts say hepatitis C is a public health threat on par with HIV... Hepatitis C Overview Hepatitis C is called a silent epidemic because many people are unaware they carry this virus of the liver. But experts say hepatitis C is a public health threat on par with HIV... View more videos... Most Popular Categories cancer cardiovascular dermatology hiv nutrition diabetes obesity pediatrics psychology neurology symptoms of a stomach virus alcohol urology breast cancer Coxackie Virus women's health infectious diseases respiratory sexual health gastrointestinal pain Virus Immunity pregnancy bones medical devices medicare depression prostate smoking alzheimer's allergy sleep biology genetics eye health sports medicine hypertension abortion health insurance autism stem cell research adhd liver disease multiple sclerosis arthritis pharma industry seniors dentistry it nursing blood fertility Flu Burung Virus Definition |
| Why Are T Cells Tolerant To Hepatitis B Virus? Health News Health Videos Forum Advertise Contact News Archive [link] Web Wikipedia Medical Dictionary [link] login | register Liver Disease / Hepatitis News Useful Links Video Library Why Are T Cells Tolerant To Hepatitis Free Trial Virsion Anti Virus B Virus? Main Category: Liver Disease / Hepatitis Article Date: 15 Oct 2008 - 2:00 PDT email to a friend printer friendly view Myrcar Virus / is a virus an organism write opinions rate article Current Article Ratings: Patient / Public: 5 (1 votes) Health Professional: Article Opinions: 0 posts The level of PD-1 expression has been proved by recent studies to be Mac Virus Dns Server positively correlated ebola virus history with the extent of HBV-specific T cell impairments. However, the degree of T cell exhaustion which affects the disease statuses Virus Cannot Be Cleaned Or Deleted of hepatitis B patients has so far been only evaluated in restricted and small groups of patients between those with established chronicity and subjects with acute HBV infection. Besides, whether levels of PD-1 expression on T cells differ between acute exacerbation of hepatitis B and chronic HBV infected patients is still unknown. A research article published in the World Journal of Gastroenterology addresses this question. The research team led by Shu-Ling Zhang from Tongji Medical College of Huazhong University of Science and Technology in China examined the expression of PD-1 on antigen specific CD8+ T cells in peripheral blood of chronic hepatitis B (CHB) and acute exacerbation of hepatitis B (AEHB) patients. They found that the levels of PD-1 on total CD8+ T cells in CHB patients were significantly higher than those in AEHB patients and healthy individuals. Conversely, lower frequencies of HBV-specific CD8+ T cells were detected in samples from chronic patients compared to AEHB patients. Our results confirmed reports that HBV specific CD8+ T-cell responses in peripheral blood were intensified in samples from AEHB patients than in those from patients with chronic hepatitis who remains viral persistence. Besides, there was a significant positive correlation between HBV viral load and percentage of PD-1 expression on CD8+ T cells in CHB and AEHB group of subjects. However, PD-1 expression was not in association with disease flare-ups indicator alanine aminotransferase (ALT). This study clarified the correlation between PD-1 expression and two different HBV infection statuses. ---------------------------- Article adapted by Medical News Today from original press release. ---------------------------- Reference: Ye P, Weng ZH, Zhang SL, Zhang JA, Zhao L, Dong JH, merca virus Jie SH, Pang R, Wei RH. PD-1 expression is associated with the disease statuses of hepatitis B virus infection. World J Gastroenterol 2008; 14(28): 4551-4557 http://www.wjgnet.com/1007-9327/14/4551.asp Correspondence to: Shu-Ling Zhang, Department of hepatology and infectious disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei virus making programs Province, China. About World Journal of Gastroenterology World Journal of Gastroenterology (WJG), a leading international journal in gastroenterology and hepatology, has established a reputation for publishing first class research on esophageal cancer, gastric cancer, liver cancer, viral hepatitis, colorectal cancer, and H pylori infection and provides a forum for both clinicians and scientists. WJG has been indexed and abstracted in Current Contents/Clinical Medicine, Science Citation Index Expanded (also known as SciSearch) and Journal Citation Reports/Science Edition, Index Medicus, MEDLINE and PubMed, Chemical Abstracts, EMBASE/Excerpta Medica, Abstracts Journals, Nature Clinical Practice Gastroenterology and Hepatology, CAB Abstracts and Global Health. ISI JCR 2003-2000 IF: 3.318, 2.532, 1.445 and 0.993. WJG is a weekly journal published by WJG Press. The publication dates are the 7th, 14th, 21st, and 28th day of every month. WJG is supported by The National computer virus called the storm botnet Natural Science Foundation of China, No. 30224801 and No. 30424812, and was founded with the name of China National Journal of New Gastroenterology on October 1, 1995, and renamed WJG on January 25, 1998. About The WJG Press The WJG Press mainly publishes World Journal of Gastroenterology. Source: Lai-Fu Li World Journal of Gastroenterology Please rate this article: (Hover over avg anti virus free edition the stars then click to rate) Patient / Public: or Health Professional: Useful Links Email Print < Top Add to: Digg Del.icio.us Reddit Fark StumbleUpon Yahoo! HealthRanker Wikio Facebook Contact Our News Editors For any corrections of factual information, or to contact the editors please use our feedback form. Please send any medical news or health news press releases to: Back to top Back to front page List of All Medical Articles Privacy Policy Terms and Conditions © 2008 MediLexicon International Ltd News Category Menu Liver Disease / Hepatitis > Categories A-B Abortion Acid Reflux / GERD ADHD Aid / Disasters Alcohol / Addiction / Illegal Drugs Allergy Alternative Medicine Alzheimer's / Dementia Anxiety / Stress Arthritis / Rheumatology Asthma Autism Back Pain (NEW) Bio-terrorism / Terrorism Biology / Biochemistry Bipolar Bird Flu / Avian Flu Blood / Hematology Body Aches Bones / Orthopaedics Breast Cancer > Categories C-D Cancer / Oncology Cardiovascular / Cardiology Caregivers / Homecare Cervical ebpla virus Cancer / HPV Vaccine Cholesterol CJD / vCJD / Mad Cow Disease Cleft Palate Clinical Trials / Drug Trials Colorectal Cancer Complementary Medicine Compliance Conferences Cosmetic Medicine Crohn's Cystic Fibrosis Dentistry Depression Dermatology Diabetes Dyslexia > Categories E-G Ear, Nose and Throat Eating Disorders Eczema / Psoriasis (NEW) Endocrinology Epilepsy Erectile Dysfunction Eye Health / Blindness Fertility Flu / Cold / SARS GastroIntestinal / Gastroenterology Genetics Gout Gynecology > Categories H-L Headache / Migraine Health Insurance / Medical Insurance Hearing / Deafness Heart Disease (NEW) HIV / AIDS Huntingtons Disease Hypertension Immune System / Vaccines Infectious Diseases Irritable-Bowel Syndrome IT / Internet / E-mail Liver Disease / Hepatitis Lung Cancer Lupus Lymphoma / Leukemia > Categories M-O Medical Devices / Diagnostics Medical Malpractice / Litigation Medical Students / Training Medicare / Medicaid / SCHIP Men's health Menopause (NEW) Mental Health MRI / PET / Ultrasound MRSA / Drug Resistance Multiple Sclerosis Muscular Dystrophy / ALS Neurology / Neuroscience Nursing / Midwifery Nutrition / Diet Obesity / Weight Loss / Fitness Ovarian Cancer (NEW) > Categories P-R Pain / Anesthetics Parkinson's Disease Pediatrics / Children's Health Pharma / Biotech Industry Pharmacy / Pharmacists Plastic Surgery Pregnancy / Obstetrics Premature Ejaculation Primary Care / Bee Virus General Practice Prostate / Prostate Cancer Psychology / Psychiatry Public Health Radiology / Nuclear Medicine Regulatory Affairs / Drug Approvals Rehabilitation / Physical Therapy Respiratory > Categories S-Z Schizophrenia Seniors / Aging Sexual Health / STDs Sleep / Sleep Disorders Smoking / Quit Smoking Sports Medicine / Fitness Statins Stem Cell Research Stroke Transplants / Organ Donations Tropical Diseases Tuberculosis (NEW) Urology / Nephrology Veterinary Viruses / Bacteria Water - Download A Virus Trap Air Quality / Agriculture Women's Health View full category list News Options Customized Homepage Weekly Newsletters Daily News Alerts Navigation Links Home About Us News Licensing Free Website Feeds Free Tools & Content Links Tell a Friend Accessibility Help / FAQ Hepatitis C Virus Picture Htm Article Submission Contact Us Health Professional Sites Psychiatry Urology Patient Information Hubs Bipolar Diabetes Schizophrenia Clinical Trials Latest News For Liver Disease / Hepatitis Consensus Statement On Hepatitis B To Be Released By NIH Oct. 22 15 Oct 2008 Why Are T Cells Tolerant To Hepatitis B Virus? 15 Oct 2008 Resveratrol Prevents Fat Accumulation In Livers Of 'Alcoholic' Mice 14 Oct 2008 View more news... Latest Videos for Liver Disease Hepatitis C Overview Hepatitis C is called a silent epidemic because many people are unaware they carry this virus of the liver. But experts say hepatitis C is a public health threat on par with HIV... Hepatitis C Overview Hepatitis C is called a silent epidemic because many people are unaware they carry this virus of the liver. But experts say hepatitis C is a public health threat on par with HIV... View more videos... Most Popular Categories cancer cardiovascular dermatology hiv nutrition diabetes obesity pediatrics psychology neurology alcohol urology breast cancer women's health infectious diseases respiratory sexual health gastrointestinal pain pregnancy bones medical devices medicare depression prostate smoking alzheimer's allergy sleep biology genetics eye health sports medicine hypertension abortion health insurance autism stem cell research adhd liver disease multiple sclerosis arthritis pharma industry seniors dentistry it nursing blood fertility |