Fuyutsuki's monologue.
Voice of university students: Professor! Fuyutsuki Sensei!
Fuyutsuki: They also said "Fuyutsuki Sensei..."
Hikari Horaki who was dead stands in front of Fuyutsuki.
Hikari: Fuyutsuki Sensei! Are you sick?
Fuyutsuki: Yes... I have a lot of things to make me have a stomachache.
Hikari: What is the name of the tablet?
Fuyutsuki: Gaster 10.
Hikari: What for?
Fuyutsuki: It is a pill for stomachache. In the first place, it is for peptic ulcer. It inhibits secretion of acid in the stomach. It is called H2 blocker.
Hikari: H2?
Fuyutsuki: Asuka knows it... Well, it means histamine receptor. It mainly consists of two kinds of receptors. Histamine is a kind of amine from the living body. One receptor is related with sneezing of pollinosis. It is called Histamine H1 receptor. The other is related with peptic ulcer. It is called H2 receptor. H2 receptors are located at stomach and duodenum.
Fuyutsuki had specialized in pharmacology before he studied abstract biology. He studied histamine receptor in 1984. Then some H2 blockers, for example cimetidine and ranitidine had been developed in foreign countries. They were also used in Japan as a remedy for peptic ulcer.
Fuyutsuki: Yamanouchi Pharmaceutical in Japan developed famotidine. It is Gaster. It was very popular as a national H2 blocker. Yamanouchi grew up into a major.
Hikari: It is a great drug, isn't it?
Fuyutsuki: Because of inhibition of secretion of acid. But the first choice at present is proton pump inhibitor. Medical doctors will be interested in new drugs. H2 blockers also inhibit symptoms of gastric cancer. So H2 blocker prevents doctors from diagnosing users as gastric cancer.
Hikari: Do you know any other national drugs?
Fuyutsuki: An example is pravastatin by Sankyo. Sankyo also made a great advance. The drug is HMG CoA reductase inhibitor. It inhibits biosynthesis of cholesterol. It is a special remedy for hyperlipemia. It is Mevalotin.
Hikari: Does it have any weak point?
Fuyutsuki: It is so effective that it makes a patient suffering from liver diseases a immoderate lower level of cholesterol in the blood. Why do you know it?
Hikari: Do human beings need drugs?
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