Influenza Annual Reports Diagnosis Vaccination and Treatment Surveillance Epidemiology Other seasonal respiratory illnesses General Influenza Annual Reports Crofts JP, Joseph CA, Zambon M, Ellis J, Fleming DM, Watson JM. Influenza survellance in the United Kingdom October 2002 to May 2003. Commun Dis Rep CDR Suppl [online] 2004 [cited 8 March 2004]; 14 (1): 1-9. (95 KB) Crofts JP, Goddard NL, Joseph CA, Zambon M, Ellis J, Fleming DM et al. Influenza surveillance in the United Kingdom: October 2001 to May 2002. Commun Dis Rep CDR Suppl 2002; 12 (1): 1-7. Goddard NL, Joseph CA, Zambon M, Nunn M, Fleming D, Watson JM. Influenza surveillance in the United Kingdom:October 2000 to May 2001. Commun Dis Rep CDR Suppl 2001; 11(Suppl 1): 1-7. Goddard NL, Joseph CA, Zambon M, Nunn M, Fleming D, Watson JM. Influenza surveillance in England and Wales: October 1999 to May 2000. Commun Dis Public Health 2000; 3: 261-6. Whiting P, Joseph CA, Zambon M, Nunn M, Fleming D, Watson JM. Influenza activity in England and Wales: October 1998 to June 1999. Commun Dis Public Health 1999; 2: 273-9. Dedman DJ, Zambon M, Van Buynder P, Fleming DM, Watson JM, Joseph CA. Influenza Surveillance in England and Wales: October 1997 - June 1998. Commun Dis Public Health; 1998; 1: 244-51. Dedman D, Joseph CJ, Zambon MC, Fleming DM, Watson JM. Influenza Surveillance in England and Wales. Oct 1996 - June 1997. Comm Dis Rep CDR Rev 1997; 7: 212-9. Hutchinson EJ, Joseph CA, Zambon MC, Fleming DM, Watson JM. Influenza Surveillance in England and Wales. October 1995 - June 1996. Comm Dis Rep CDR Rev 1996; 6: 163-9. Hutchinson EJ, Joseph CA, Chakraverty P, Zambon M, Fleming DM, Watson JM. Influenza surveillance in England and Wales October 1994 - June 1995. Comm Dis Report CDR Rev 1995; 6:163-9. Influenza publications Diagnosis Ellis JS. Influenza A H1N2 viruses. ESWI Bulletin 16. pg 5. Crowcroft NS, Booy R, Harrison T, Spicer L, Britto J, Mok Q, Heath P, Murdoch I, Zambond M, George R, Miller E. Severe and unrecognised Pertussis in UK infants. Archiv Dis Childhood. 2003; 88: 802-806. McKimm-Breschkin JL, Trivedi T, Hamspon AH, Hay A, Klimov A, Tashiro M, Hayden F and Zambon M on behalf of the Neuraminidase Inhibitor Susceptibility Network (NISN). Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir. AntiMicrobial agents & Chemotherapy. 2003; 47: 2264 – 2272 Stephenson I, Wood JM, Nicholson KG, Zambon MC. Change in Receptor Specificity of Erythrocytes affects Haemagglutination-Inhibition Detection of Antibodies to Avian Influenza Haemagglutinin J Med Virol .2003; 70: 391-8 Paget WJ, Zambon M, Uphoff H, Bartelds A on behalf of EISS. Declining influenza activity and no indication that media coverage associated with SARS has led to an increase in ILI/ARI consultations in family practice. Eurosurveillance Weekly 2003: 15 Stephenson I, Nicholson KG, Colegate A, Podda A, Wood J, Ypma E, Zambon MC .Boosting immunity to influenza H5N3 with MF59 adjuvanted H5N3 A/Duck/Singapore/97 vaccine in a primed human population. Vaccine Apr 2003.; 2;21(15):1687-93. Ellis JS, Alvarez-Aguero A, Gregory V., YP Lin, A Hay, MC Zambon. Influenza AH1N2 viruses and their impact during the 2001-02 influenza season in the United Kingdom. Emerging Infections. 2003; 9: 304 –310. Loeffen WLA, Heinen PP, Bianchi ATJ, Hunneman WA, Verheijden JHM. Effect of maternally derived antibodies on the clinical signs and immune response in pigs after primary and secondary infections with an influenza H1N1 virus. Vet Immunol Immunopathol. 2003;92(1-2):23-35. Loeffen WL, Nodelijk G, Heinen PP, van Leengoed LA, Hunneman WA, Verheijden JH. Estimating the incidence of influenza-virus infections in Dutch weaned piglets using blood samples from a cross-sectional study. Vet Microbiol. 2003;91(4) : 295-308. Mitchell JA, Green TD, Bright RA, Ross TM. Induction of heterosubtypic immunity to influenza A virus using a DNA vaccine expressing hemagglutinin-C3d fusion proteins. Vaccine. 2003; 21: 902-914. Harnden A, Sheppard S, Brueggmann A, White J, Crook D, Zambon M, Mant D . Near Patient Testing for influenza in primary care: a prospective case series. BMJ 2003; 326: 480. N.T. Wetherall, T. Trivedi J. Zeller, C. Hodges-Savola, F.G. Hayden, M. Zambon, (2003). Evaluation of Neuraminidase Enzyme Assays using different substrates to measure the susceptibility of Influenza Clinical Isolates to Neuraminidase Inhibitors. J Clin Micro 2003; 41: 742-750. Wood, JM, Melzack D, Newman RW, Major DL, Zambon MC, Nicholson KG, et al. A single radial haemolysis assay for antibody to H5 haemagglutinin. In: Osterhaus A, Cox N, Hampson A, editors. Options for the Control of Influenza IV. International Congress Series 2001; 1219: 761-766. Elsevier. Zambon MC, Ellis JS. Molecular methods for diagnosis of influenza. In: Osterhaus A, Cox N, Hampson A, editors. Options for the Control of Influenza IV. International Congress Series 2001; 1219: 267-73. Elsevier. Ellis JS Zambon MC . A heteroduplex mobility assay for the detection of influenza A strains from different species. J Clin Micro 2001; 39: 4097-4102. Zambon M, Hayes J, Webster A, Newman R, Keene O. Diagnosis of influenza in the community: relationship of clinical diagnosis to confirmed virological, serologic, or molecular detection of influenza. Arch Intern Med 2001; 161: 2116-22. Boon AC, French AM, Fleming DM, Zambon MC. Detection of influenza A subtypes in community-based surveillance. J Med Virol 2001; 65: 163-70 Andrade HR, Zambon MC. Different Diagnostic Methods for the Detection of Influenza Epidemics. Epidemiol Infect 2000; 124: 515-22. Zambon MC. Cell Culture for Surveillance of Influenza. In Inactivated influenza vaccines prepared in cell culture. Developments in Biological Standardisation. 1999; 98: 65-71. Basel Karger. Stockton J, Ellis JS, Saville M, Clewley J, Zambon MC. Multiplex PCR for the detection of influenza and RSV in respiratory specimens. J Clin Microbiol 1998; 36: 2990-5. Zambon MC. Laboratory Diagnosis of Influenza, In :Textbook of Influenza. Webster RG, Hay AJ, Nicolson K, editors. Oxford Blackwell, 1998. 291-313. Ellis JS, Brown WG. PCR for the detection of influenza viruses in clinical material. In: JR Stephenson & A Warnes, editors. Diagnostic Virology Protocols. Humana Press, New Jersey, 1998. 119-27. Zambon MC. Laboratory containment for influenza A H5N1: level 2, level 3 or level 3+. Commun Dis Public Health 1998; 1: 71-2. Ochert A, Slomka MJ, Ellis J, Teo CG. Use of Chelex 100TM in the extraction of viruses from diverse cell-free clinical samples for PCR. In: A Rolfs, I Weber-Rolfs & U Finckh, editors. Methods in Amplification. Plenum Press, New York 1994: 47-53. Vaccination and Treatment JosephCA, Goddard NL. Influenza vaccine uptake in the elderly: Results from a rapid assessment of the effectiveness of new government policy in England for the winters 2000/01 and 2001/02.Vaccine 2003; 21 (11-12): 1137-1148. Wood JM, Nicholson KG, Zambon MC, Hinton R, Major DL, Newman RW, et al. Developing vaccines against potential pandemic influenza vaccines. In: Osterhaus A, Cox N, Hampson A, editors. Options for the Control of Influenza IV. International Congress Series Elsevier, 2001; p751-61. Nicholson KG, Colegate AE, Podda A, Stephenson I, Wood J, Ypma E, et al. Confronting a potential H5N1 pandemic: a randomised controlled trial of conventional and MF59 adjuvanted influenza A/Duck/Singapore/97 (H5N3) surface antigen vaccine. Lancet 2001; 357: 1937-43. Lawson TM, Man S, Williams S, Boon ACM, Zambon MC, Borysiewicz. Influenza A antigen exposure selects dominant V (beta) 17(+) human CD8 (+) cytotoxic T cell responses. Int Immunol ; 2001; 13: 1373-81. Gandhi MK, Egner W, Sizer L, Inman I, Zambon M, Craig JIO, et al. Antibody responses to vaccinations given before two years post transplant are similar between autologous peripheral stem cell and bone marrow transplant recipients. Bone Marrow Transplantation 2001; 28: 775-81. Zambon M, Hayden FG. Position statement: global neuraminidase inhibitor susceptibility network. Antiviral Res 2001; 49: 147-56. Nicholson KG, Colegate AE, Podda A, Stephenson I, Wood J, Ypma E, et al. Safety and antigenicity of non-adjuvanted and MF59-adjuvanted influenza A/Duck/Singapore/97 (H5N3) vaccine: a randomised trial of two potential vaccines against H5N1 influenza. Lancet 2001; 357: 1937-43. Chisholm JC, Devine T, Charlett A, Pinkerton CR, Zambon M. Response to influenza immunisation during treatment for cancer. Arch Dis Child 2001; 84: 496-500. Elliot A, Ellis J. Influenza prevention and treatment - an update. The Pharmaceutical Journal 2000; 265: 446-5. Roberston JD, Nagesh K, Jowitt SN, Dougal M, Anderson H, Mutton K, et al. Immunogenicity of vaccination against influenza, Streptococcus pneumoniae and Haemophilus influenzae type B in patients with multiple myeloma. Br J Cancer 2000; 82: 1261-5. Zambon MC. Active and passive immunisation against respiratory syncytial virus. Rev Med Virol 1999; 9: 227-36. Anderson H, Petrie K, Berrisford C, Charlett A, Thatcher N, Zambon MC. Seroconversion after influenza vaccination in patients with lung cancer. Br J Cancer 1999; 80: 219-20. Pillay D, Zambon M. Antiviral drug resistance BMJ 1998; 317: 660-3. Irish C, Ali M, Gillham C, Joseph CA, Watson JM. Influenza vaccine uptake and distribution in England and Wales, July 1989 -June 1997. Health Trends 1998; 30: 52-5. Lyall EGH, Charlett A, Watkins P, Zambon MC. Response to influenza virus vaccine in young children vertically infected with HIV. Arch DisChild 1997; 76: 215-8. Surveillance Goddard NL, Joseph CA, Watson JM, Ellis J, Zambon MC. Three years of low influenza activity - no reason for complacency. Comm Dis Pub Health 2003;6: 128-132. Watson JM, Zambon MC. NHS Direct and influenza epidemics (rapid response). BMJ 2003. Available at <http://bmj.com/cgi/eletters/325/7377/1397#28865> JS Ellis, A Alvarez-Aguero, V. Gregory, YP Lin, A Hay, MC Zambon. Influenza AH1N2 viruses and their impact during the 2001-02 influenza season in the United Kingdom. Emerging Infections 2003; 9: 304 -310. Gregory V, Bennett M, Orkhan MH, Hajjar AL, Varsano N, Mendelson E. Emergence of influenza A H1N2 reassortant viruses in the human population during 2001. Virology 2002; 300: 1-7. Paget WJ, Meerhoff TJ, Goddard NL. Mild to moderate influenza activity in Europe and the detection of novel A (H1N2) and B viruses during the winter of 2001-2002. Euro Surveill. 2002 Nov;7(11):147-57 Reagan CM, Johnstone F, Joseph CA, Urwin M. Local Surveillance of influenza in the United Kingdom: from sentinal general practices to sentinel cities? Commun Di. Public Health 2002; 5, (1): 17-22. Cooper DL, Smith GE, Hollyoak VA, Joseph CA, Johnson L, Chaloner R. Use of NHS Direct calls for surveillance of influenza - a second years's experience. Commun Dis Public Health 2002; 5, (2): 127-31. Paget WJ, Aguilera JF (on behalf of EISS). Influenza Pandemic Planning in Europe. Eurosurveillance 2001; 6: 136-40. Manugerra JC, Mosnier A, Paget WJ (on behalf of EISS). Monitoring of influenza in the EISS European network member countries from October 2000 to April 2001. Eurosurveillance 2001; 6 127-35. Boon ACM, French A, Fleming DM, Zambon MC. Detection of Influenza A in community based surveillance. J Med Virol 2001; 65 163-70. Harcourt S, Smith G, Hollyoak V, Joseph CA et al. Can calls to NHS Direct be used for syndromic surveillance? Commun Dis Public Health (2001); 4, (3): 178-88. Manuguerra JC, Mosnier A (on behalf of EISS). Surveillance of influenza in Europe from October 1999 to February 2000. Eurosurveillance 2000; 5: 63-8. Zambon M, Joseph CA. The PHLS Pandemic Plan. London: PHLS 2000. Watson JM. Surveillance of Influenza. In: Textbook of influenza. Webster RG, Hay AJ, Nicholson K, editors. Oxford Blackwell, 1998. p207-16. Ellis J, Joseph CA, Zambon M. Fifty years of influenza surveillance. Commun Dis Public Health 1999; 2: 81-82. Zambon MC. Sentinel surveillance of influenza in Europe. Eurosurveillance 1998; 3: 29-31. Dedman DJ, Watson JM. The use of thresholds to describe influenza activity. Microbiology Digest 1997; 14: 206-8. Ellis JS, Fleming DM, Zambon MC. Multiplex RT-PCR for Surveillance of influenza in England 1995/1996. J Clin Micro 1997; 35: 2076-2082. Zambon MC. Influenza activity - United States and Worldwide, 1996-1997 season and composition of the 1997-98 influenza vaccine. J Am Med Assn 1997; 277: 1666-7. Zambon M. Update: Influenza activity - United States and worldwide 1995-96 season and composition of the 1997-1998 influenza vaccine. J Am Med Ass. 1996; 275: 1467-8. Zambon MC, Ellis JS, Sadler CJ, Fleming DM. The use of multiplex PCR for typing and subtyping influenza viruses in a sentinel surveillance scheme in the UK. In: Brown, Hampson, Webster, editors. Options for the control of Influenza III. International Congress Series Elsevier. 1996. Epidemiology Zambon MC. Shifty drifter up to no good. Lancet Infect Dis 2002; 2: 269-70. Zambon MC. Influenza and respiratory syncytial virus. Medicine: 29: 118-22. Watson JM, Goddard N, Joseph C, Zambon MC. Influenza: the impact of the 1999/2000 epidemic on morbidity and mortality in the UK. In: Osterhaus ADME, editor. Options for the Control of Influenza. Elsevier, 2001. p21-3. Zambon MC, Stockton JD, Clewley JP, Fleming DM. Influenza or RSV? Community cases of influenza like illness. Lancet 2001; 358 1410-6. Fleming DM, Zambon MC, Bartelds AIM. Population estimates of persons presenting to general practitioners with influenza like illness 1987-1996: a study of the demography of influenza-like illness in sentinel practice networks in England and Wales, and in The Netherlands. Epidemiol Infect 2000; 124: 254-3. Zambon MC. Epidemiology and pathogenesis of influenza. J Antimicrobial Chemotherapy 1999; 44 Topic B: 3-9. Fleming DM, Zambon MC, Bartelds AIM, Jong JC. The duration and magnitude of influenza epidemics: a study of surveillance data from sentinel general practices in England, Wales and the Netherlands. Euro J Epidemiology 1999; 15: 467-73. Ellis J, Zambon M. Molecular investigation of an outbreak of influenza. Eur J Epidemiol. 1997; 13: 1-4. <> Ellis JS, Sadler CJ, Laidler P, Rebelo de Andrade H, Zambon MC. Analysis of Influenza A H3N2 strains isolated in England 1995-1996 using PCR restriction. J Med Virology 1997; 51: 234-41. Watson JM, Dedman D, Joseph C, Zambon M, Timbury M. Influenza types and patient population. Lancet 1995; 346: 515-6. Ellis JS, Chakraverty P, Clewley JP. Genetic and antigenic variation in the haemagglutinin of recently circulating human influenza A (H3N2) viruses in the United Kingdom. Arch Virol 1995; 140: 1889-904. Irving WL, James DK, Stephenson T, Laing P, Jameson C, Oxford JS, et al. Influenza infection in the second and third trimesters of pregnancy: a clinical and seroepidemiological study. BJOG 2000; 107:1282-9. Other seasonal respiratory illnesses Stockton J, Stephenson I, Fleming DM, Zambon M. Human. Metapneumovirus as a cause of community-acquired respiratory illness. Emerg Infeci Dis 2002; 8 (9): 897-901. Zambon MC, Stockton JD, Clewley JP, Fleming DM. Contribution of influenza and respiratory syncytial virus to community cases of influenza-like illness: an observational study. Lancet 2001;358: 1410-6. Muller-Pebody B, Edmunds WJ, Zambon MC, Gay NJ, Crowcroft NS. Contribution of RSV to bronchiolitis and pneumaonia-associated hospitalisations in English children, April 1995-March 1998. Epidemiol Infect 2002; 129, 99-106. Crowcroft NS, Cutts F, Zambon MC. Respiratory Syncytial virus: An underestimated cause of respiratory infection, with prospects for a vaccine. Commun Dis Public Health 1999; 2: 234-41. Laurichesse H, Dedman D, Watson JM, Zambon MC. Epidemiological features of Parainfluenza virus infections. Laboratory surveillance in England and Wales 1975-1997. Eur J Epidem 1999; 15: 495-484. Zambon MC, Bull T, Sadler CS, Goldman JM, Ward KN. Molecular Investigation of two consecutive outbreaks of parainfluenza 3 on a Bone Marrow Transplant Unit J. Clin Microbiol 1998; 36: 2289-93. Zambon M. Update on respiratory syncytial virus vaccination and immunoprophylaxis. Current Medical Literature, Virology 1996; 5: 99-107. General Ison MG, Mills J, Openshaw P, Zambon M C, Osterhaus ADME, Hayden FG. Current Research on Respiratory Viral Infections: Fourth International Symposium on Respiratory Viruses. Antiviral Res 2002; 55 227-278. Zambon MC.The pathogenesis of influenza in humans. Rev Med Virol 2001; 11: 227-241. Fleming DM, Zambon M. Update in influenza and other viral pneumonias. Curr Opin Infect Dis 2001; 14: 199-204. Advances in Influenza. Editor Zambon MC. International Medical Forum 104. Oxford: Blackwell Science, 1999. Stockton J S, Zambon MC. The Influenza Virus. Hospital Medicine 1999; 60: 724-730.