Degenerative arthritis bilaterally
On the other hand, the only RCT of acupuncture for rheumatoid arthritis employed too small a sample size for any statistically significant result to emerge. degenerative arthritis bilaterally Juvenille rhumatoid arthritis. Physicians should be willing to discuss with their patients the potential use of acupuncture as a means of pain management. Also the NIH consensus panel on acupuncture stated that the occurrence of adverse events during needle manipulation has been documented to be extremely low. (top of section)(top of page) Dietary Supplementation GlucosamineChondroitin SulfateGlucosamineGlucosamine has been studied as a therapeutic agent for decades, but only recently has become popular for treating osteoarthritis. degenerative arthritis bilaterally Degenerative arthritis bilaterally. This is in part due to the 1994 Dietary Supplement and Health Education Act and the reaction to the book The Arthritis Cure. Glucosamine is an aminomonosaccharide found in articular cartilage. In vitro studies using human chondrocytes showed that glucosamine also stimulated proteoglycan synthesisref 3. degenerative arthritis bilaterally Exercises for arthritis. This potential mechanism is attractive as treatment for osteoarthritis because in OA proteoglycan production does not keep pace with its loss, resulting in a net loss of cartilage matrix. High doses of oral glucosamine administered to rats had a mild anti-inflammatory effect in adjuvant-induced arthritis. Reicheltref 4) reported a large multicentric, randomized, double blind, placebo-controlled trial of glucosamine sulfate in osteoarthritis of the knee in 1994. Diagnosis was made based on the clinical and radiological criteria of Lequesne. All patients were symptomatic with pain at rest or on movement and had functional limitations. One hundred fifty-five patients were randomized to receive either 400 mg of glucosamine sulfate or placebo intramuscularly twice weekly for 6 weeks. Assessment occurred on days 3 and 7 each week during the study period and at 2 weeks following the conclusion of the study. A positive response to drug therapy was defined as a decrease in the Lequesne index of 3 points and the investigator's judgment of good or moderate effects. All patients in the study were symptomatic for at least 6 months prior to the study. Nonsteroidal anti-inflammatory drugs, corticosteroids, or other arthritis therapies were not allowed to be used by the subjects, except for acetaminophen as a rescue medication. Subjects needing acetaminophen for pain control were automatically classified as non-responders.
Degenerative arthritis bilaterally
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