Metabolic Enzymes and Pathways; Signaling Pathways  


Enzymes and Enzyme Nomenclature

Database name

Description

BRENDA

Enzyme names and biochemical properties

ENZYME

Enzyme nomenclature and properties

Enzyme Nomenclature

IUBMB Nomenclature Committee recommendations

EzCatDB

Enzyme Catalytic Mechanism Database

IntEnz

Integrated enzyme database and enzyme nomenclature

MACiE

Mechanism, annotation and classification in enzymes: enzyme reaction mechanisms

PDBrtf

Representation of target families of enzymes in PDB

Pathguide

A listing of pathway, signal transduction and protein-protein interaction databases

SCOPEC

Mapping of catalytic function to domain structure

Metabolic Pathways

Database name

Description

BioSilico

Integrated access to various metabolic databases

KEGG Pathway

Metabolic and regulatory pathways in complete genomes

Lipid MAPS

Lipid metabolites and pathways strategy

MetaCyc

Metabolic pathways and enzymes from various organisms

PathDB

Biochemical pathways, compounds and metabolism

UM-BBD

University of Minnesota biocatalysis and biodegradation database

Protein-protein Interactions

Database name

Description

3DID

3D interacting domains: Domain-domain interactions in proteins with known 3D structures

AffinDB

Affinity data for protein-ligand complexes

DDIB

Database of domain interactions and binding

DIP

Database of interacting proteins: Experimentally-determined protein-protein interactions

DRC

Database of ribosomal crosslinks

hp-DPI

Database of protein interactions in Helicobacter pylori

HPID

Human protein interaction database

IntAct project

Protein-protein interaction data

Inter-Chain Beta-Sheets

Protein-protein interactions mediated by interchain beta-sheet formation

InterDom

Putative protein domain interactions

KDBI

Kinetic data of bio-molecular interactions

OPHID

Online predicted human interaction database

PDZBase

Protein-protein interactions involving PDZ domains

Protein-protein interfaces

Interacting residues in protein-protein interfaces in PDB

PINdb

Proteins interacting in nucleus (human and yeast)

POINT

Prediction of human protein-protein interactome

PSIbase

Interaction of proteins with known 3D structures

pSTIING

Protein signalling, transcriptional interactions and inflammation networks gateway

STRING

Predicted functional associations between proteins

Signaling Pathways

Database name

Description

aMAZE

A system for the annotation, management, and analysis of biochemical and signalling pathway networks

BIND

Biomolecular interaction network database

BioCarta

Online maps of metabolic and signaling pathways

BioGrid

Genetic and physical interactions in yeast, worm and fly

BRITE

Biomolecular relations in information transmission and expression, part of KEGG

Cyclonet

A database on cell cycle regulation in eukaryotes

EndoNet

Information on endocrine networks

GeneNet

Database on gene network components

Reactome

A database of metabolic and signaling pathways

ROSPath

Reactive oxygen species (ROS) signaling pathway

STCDB

Signal transductions classification database

TRANSPATH

Gene regulatory networks and microarray analysis