Rift ValleyFever

Definition

Rift Valley fever (RVF) is an acute, fever-causing viral disease that affects domestic animals (such as cattle, buffalo, sheep, goats, and camels) and humans. RVF is most commonly associated with mosquito-borne epidemics during years of heavy rainfall. The disease is caused by the RVF virus, a member of the genus Phlebovirus in the family Bunyaviridae. The disease was first reported among livestock by veterinary officers in Kenya in the early 1900s.

Symptoms

RVF virus can cause several different disease syndromes. People with RVF typically have either no symptoms or a mild illness associated with fever and liver abnormalities. However, in some patients the illness can progress to hemorrhagic fever (which can lead to shock or hemorrhage), encephalitis (inflammation of the brain, which can lead to headaches, coma, or seizures), or ocular disease (diseases affecting the eye). Patients who become ill usually experience fever, generalized weakness, back pain, dizziness, and extreme weight loss at the onset of the illness. Typically, patients recover within two days to one week after onset of illness. Approximately 1% of humans that become infected with RVF die of the disease.

Complications: The most common complication associated with RVF is inflammation of the retina (a structure connecting the nerves of the eye to the brain). As a result, approximately 1% - 10% of affected patients may have some permanent vision loss.

Transmission

Humans can get RVF as a result of bites from mosquitoes and possibly other blood-sucking insects that serve as vectors. Humans can also get the disease if they are exposed to either the blood or other body fluids of infected animals. This exposure can result from the slaughtering or handling of infected animals or by touching contaminated meat during the preparation of food. Infection through aerosol transmission of RVF virus has resulted from contact with laboratory specimens containing the virus. DiagnosisClinical presntation of symptoms.TreatmentThere is no established course of treatment for patients infected with RVF virus. However, studies in monkeys and other animals have shown promise for ribavirin, an antiviral drug, for future use in humans. Additional studies suggest that interferon, immune modulators, and convalescent-phase plasma may also help in the treatment of patients with RVF. PreventionA person’s chances of becoming infected can be reduced by taking measures to decrease contact with mosquitoes and other blood-sucking insects through the use of mosquito repellents and bednets. Avoiding exposure to blood or tissues of animals that may potentially be infected is an important protective measure for persons working with animals in RVF-endemic areas.

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Protection from Chemical Hazards

Anthrax Decontamination

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Biological Agents:

Anthrax/Botulism/Brucellosis/Campylobacteriosis/Cholera/Dengue Fever/Ebola Fever/E. Coli/Hanta Fever/Lassa Hemorrhagic Fever/Legionellosis/Marburg Hemorrhagic Fever/ Plague/Rift Valley Fever/Smallpox/Streptococcus/Tularemia/West Nile Fever

 Chemical Agents:

Sarin/Tabun/VX

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