Since 1989, the Human Genome Organisation (HUGO) attempts to ensure that for each gene there is one name and one symbol. The resulting standard nomenclature is, however, poorly applied in clinical studies, which impairs the efficient retrieval of information. This lack of support is reflected in the present survey of 303 articles (from 106 journals) reporting on disseminated tumour cell detection.
HUGO gene symbol (number of abstracts citing this symbol / total number of abstracts citing the marker) | HUGO gene name (number of abstracts citing this name / total number of abstracts citing the marker) | Frequently-used non-standard names and symbols(“aliases”) | Type of cancer |
| | |
ANKRD30A (0 / 5) | Ankyrin repeat domain 30A (0 / 5) | B726; B726P; NY-BR-1 | Breast |
CEACAM5 (2 / 64) | Carcinoembryonic antigen-related cell adhesion molecule 5 (2 / 64) | Carcinoembryonic antigen; CEA | Breast, Colorectal, Esophagus, Gastric, Head & Neck, Lung, Pancreas, Thyroid |
DCT (0 / 2) | Dopachrome tautomerase (0 / 2) | Tyrosinase-related protein-2; TRP-2 | Melanoma |
EGFR (14 / 15) | Epidermal growth factor receptor (15 / 15) | EGF-R | Bladder, Breast, Cervical, Colorectal, Head & Neck, Lung, Prostate |
FOLH1 (0 / 6) | Folate hydrolase 1 (0 / 6) | Prostate-specific membrane antigen; PSM; PSMA | Prostate |
GUCY2C (0 / 4) | Guanylate cyclase 2C (0 / 4) | Guanylyl cyclase C; guanylylcyclase C; GCC | Colorectal |
KLK3 (1 / 14) | Kallikrein-related peptidase 3 (1 / 14) | Prostate specific antigen; prostate-specific antigen; PSA | Prostate |
KRT7 (0 / 5) | Keratin 7 (0 / 5) | Cytokeratin 7; CK7; CK-7 | Breast, Esophagus, Lung, Ovary |
KRT19 (1 / 77) | Keratin 19 (1 / 77) | Cytokeratin 19; cytokeratin-19; CK19; CK-19 | Bladder, Breast, Cervical, Colorectal, Esophagus, Gastric, Head & Neck, Lung, Ovary, Pancreas, Thyroid |
KRT20 (1 / 68) | Keratin 20 (1 / 68) | Cytokeratin 20; Cytokeratin-20; CK20; CK-20; CK 20 | Bladder, Breast, Cervical, Colorectal, Esophagus, Gastric, Head & Neck, Lung, Ovary, Pancreas, Thyroid |
MLANA (0 / 17) | Melan-A (7 / 17) | Melanoma antigen recognized by T cells 1; MART1, MART-1 | Melanoma |
MUC1 (13 / 20) | Mucin 1 (12 / 20) | Mucin type I; polymorphic epithelial mucin; EMA; MUC-1; MUC 1 | Breast, Colorectal, Gastric, Lung |
MUCL1 (0 / 2) | Mucin-like 1 (0 / 2) | Small mucin-like protein; small breast epithelial mucin; BS106; SBEM | Breast |
OR51E2 (0 / 2) | Olfactory receptor, family 51, subfamily E, member 2 (0 / 2) | Prostate-specific G protein coupled receptor; prostate-specific gene with homology to G protein receptor; PSGR; STAG1/PMEPA1 | Prostate |
PLUNC (0 / 2) | Palate, lung and nasal epithelium carcinoma associated (0 / 2) | Lung-specific X-protein; lunx | Lung |
SCGB2A1 (0 / 8) | Secretoglobin family 2A, member 1 (0 / 8) | Mammaglobin B; mammaglobin-B; mammaglobin 2; mamB; MGB2 | Breast |
SCGB2A2 (0 / 34) | Secretoglobin family 2A, member 2 (0 / 34) | Mammaglobin; mammaglobin A; mammaglobin 1; MAM; mam; hMAM; hMAM-A; MG; MGB1; MMG | Breast |
SERPINB3 (0 / 4) | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 (0 / 4) | Squamous cell carcinoma antigen 1; SCCA1; SCC | Esophagus, Head & Neck |
SERPINB4 (0 / 1) | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4 (0 / 1) | Squamous cell carcinoma antigen 2; SCCA2 | Esophagus, Head & Neck |
SERPINB5 (0 / 12) | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 (0 / 12) | Maspin; MAS | Breast |
SILV (0 / 3) | Silver homolog (mouse) (0 / 3) | Gp100; GP-100 | Melanoma |
TACSTD1 (3 / 13) | Tumor-associated calcium signal transducer 1 (3 / 13) | Epithelial glycoprotein 2; epithelial glycoprotein 40; EGP40; EGP2; KS1/4; GA733-2 | Breast, Colorectal, Esophagus, Lung |
TERT (0 / 13) | Telomerase reverse transcriptase (11 / 15) | hTERT; h-TERT | Breast, Colorectal, Liver, Melanoma, Stomach, Thyroid |
TFF1 (1 / 4) | Trefoil factor 1 (1 / 4) | PS2 | Breast |
UCHL1 (0 / 2) | Ubiquitin carboxyl-terminal esterase L1 (0 / 2) | Ubiquitin thiolesterase; PGP 9.5 | Lung |