ALL
| QB |
RB |
WR |
K |
D |
| Team | Player | Years | Points | Starts | Points Per Start | ||
| 1. |  Duff Beer |  | DeAngelo Williams | 2003-2005 | 367 | 25 | 14.7 |
| 2. |  South Central |  | Steve Slaton | 2006-2007 | 343 | 21 | 16.3 |
| 3. | South Central |  | Darren McFadden | 2005-2007 | 300 | 21 | 14.3 |
| 4. |  Bite Me |  | Adrian Peterson | 2004-2006 | 294 | 22 | 13.4 |
| 5. |  Betty White |  | Ray Rice | 2006-2007 | 289 | 20 | 14.4 |
| 6. |  Headbanger |  | Mike Hart | 2005-2007 | 281 | 29 | 9.7 |
| 7. |  Burlington |  | Ian Johnson | 2006-2007 | 277 | 19 | 14.6 |
| 8. |  Pee Dee |  | James Davis | 2005-2007 | 275 | 25 | 11 |
| 9. | Headbanger |  | P.J. Hill | 2006-2007 | 267 | 19 | 14.1 |
| 10. | Betty White |  | Maurice Drew | 2004-2005 | 267 | 17 | 15.7 |
| 11. |  Cincinnati |  | Jamaal Charles | 2005-2007 | 243 | 22 | 11 |
| 12. | Cincinnati |  | Lendale White | 2004-2005 | 240 | 17 | 14.1 |
| 13. |  Palmetto St |  | Kevin Smith | 2006-2007 | 236 | 13 | 18.2 |
| 14. |  College |  | Darren Sproles | 2003-2004 | 233 | 19 | 12.3 |
| 15. | College |  | Laurence Maroney | 2004-2005 | 230 | 17 | 13.5 |
| 16. | Betty White |  | Michael Bush | 2004-2006 | 219 | 13 | 16.8 |
| 17. |  Gridiron Group |  | Dontrell Moore | 2003-2004 | 219 | 17 | 12.9 |
| 18. | College | | Reggie Bush | 2003-2005 | 217 | 18 | 12.1 |
| 19. |  Clermont | | Brian Calhoun | 2003-2005 | 209 | 15 | 13.9 |
| 20. | Pee Dee |  | Carnell Williams | 2003-2004 | 208 | 19 | 10.9 |
| 21. | Burlington |  | Chris Barclay | 2003-2005 | 206 | 23 | 9 |
| 22. |  Morristown |  | Jonathan Stewart | 2005-2007 | 204 | 24 | 8.5 |
| 23. |  Peoples U |  | Walter Reyes | 2003-2004 | 204 | 15 | 13.6 |
| 24. | Palmetto St |  | Matt Forte | 2005-2007 | 199 | 15 | 13.3 |
| 25. | Burlington |  | Yvenson Bernard | 2006-2007 | 197 | 20 | 9.8 |
| 26. | Burlington |  | Howard Jackson | 2003-2004 | 179 | 15 | 11.9 |
| 27. | Headbanger | | Chris Perry | 2003 | 179 | 12 | 14.9 |
| 28. | Morristown |  | Branden Ore | 2006-2007 | 179 | 16 | 11.2 |
| 29. | Cincinnati |  | Marshawn Lynch | 2005-2006 | 178 | 16 | 11.1 |
| 30. | Duff Beer | | Cedric Benson | 2004 | 175 | 10 | 17.5 |
| 31. | Bite Me |  | Jason Wright | 2003 | 168 | 12 | 14 |
| 32. | Pee Dee |  | Courtney Lewis | 2004-2006 | 167 | 21 | 8 |
| 33. |  Cronko | | Dontrell Moore | 2005 | 160 | 11 | 14.5 |
| 34. | Pee Dee |  | Anthony Alridge | 2007 | 158 | 10 | 15.8 |
| 35. |  Slacker | | Steven Jackson | 2003 | 153 | 11 | 13.9 |
| 36. | Duff Beer |  | Taurean Henderson | 2003-2005 | 151 | 15 | 10.1 |
| 37. | South Central |  | Chance Kretschmer | 2003-2004 | 149 | 18 | 8.3 |
| 38. | Palmetto St |  | Curtis Brown | 2005-2006 | 148 | 14 | 10.6 |
| 39. | Duff Beer |  | Jerome Harrison | 2005 | 145 | 9 | 16.1 |
| 40. | Clermont |  | Lonta Hobbs | 2003-2005 | 143 | 15 | 9.5 |