Prostaglandin H2 synthase-1

EGF-like domain (blue), amphipathic membrane binding motif (red), catalytic globular domain (grey), heme groups (brown), and arachidonic acid in its binding site (yellow).

                                                                       Introduction

Homology to other proteins

Structural comparison

3-D structures of PGHS-1 (Rasmol)

Arachidonic acid bound to COX channel

Iodosuprofen(inhibitor) bound to PGHS-1

References

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